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The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function

NCT06194955 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-04-29

No results posted yet for this study

Summary

This project will characterize the physiological effect of the hormones, GIP-, GLP-1- and GLP-2 infusions in a group of individuals that are carriers of GIP-, GLP-1- and GLP-2 receptor gene variants, respectively.

Conditions

  • Incretin Effect

Interventions

DRUG

GIP(1-42)

Infusion

DRUG

GLP-1

Infusion

DRUG

GLP-2

Infusion

OTHER

Placebo

Saline

Sponsors & Collaborators

  • Gentofte Hospital, Denmark

    collaborator UNKNOWN

  • University of Copenhagen

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-04
Primary Completion
2025-12-10
Completion
2026-04-01

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06194955 on ClinicalTrials.gov