Placental Organoids Development: Application in the Study of the Human Reproduction Pathophysiology.
NCT06893978 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2025-05-20
Summary
Placental organoids represent an in vitro 3D reconstruction model of the human placenta and of its complex cellular organization to evaluate the pharmacological effect in terms of placentation, gene expression, protein synthesis and placental secretomics.
Conditions
- Preeclampsia
- Pregnancy Loss
- Preterm Birth
- Healthy
Interventions
- DRUG
-
Placenta organoids treatment
Placenta organoids in vitro treatment with heparin, aspirin, IVIG, filgrastim and metformin
Sponsors & Collaborators
-
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
lead OTHER
Principal Investigators
-
Chiara Tersigni, MD · Fondazione Policlinico Universitario A. Gemelli, IRCCS
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-05-20
- Primary Completion
- 2027-11-30
- Completion
- 2027-11-30
Countries
- Italy
Study Locations
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