Mini-Crush Or Controlled Balloon-Crush For True Coronary Bifurcation Lesions

Summary

The mini-crush technique is one of the leading 2-stent techniques frequently applied by interventional cardiologists to treat complex bifurcation lesions. In the last 20 years, many technical innovations and iterations of mini-crush technique have been developed, and it maintains its popularity among invasive cardiologists. Moreover, mini-crush and double kissing-crush techniques have been compared in terms of clinical results in both left main and non-left main coronary bifurcation patient populations and no significant difference was found. However, the most important challenges of the mini-crush technique are the rewiring and advancement of a 1:1 non-compliant side-branch balloon after the main branch stent has been implanted. These challenges usually necessitate the use of a low profile balloon or additional support maneuvers (such as anchor balloon). Recently, a novel modified mini-crush-crush technique (controlled balloon-crush) has been introduced to the literature and is one of the most up-to-date crush techniques. The main advantage of this technique over the contemporary mini-crush technique is that the side branch can be easily rewired and the 1:1 size non-compliant balloon can easily pass through the crushed stent structure in the ostial part of the side branch. The basic rationale of this is that the crushing of the side branch stent is done in a more controlled manner (by slowly deflation of the side branch stent balloon) and this causes less disruption of the stent cells. This prospective observational study aims to assess the procedural and 1-year clinical outcomes of the contemporary mini-crush and controlled balloon-crush (modified mini-crush) double stenting techniques in patients with true coronary bifurcation lesions.

Conditions

• Coronary Bifurcation Lesions
• Death
• Myocardial Infarction (MI)
• Stent Thrombosis
• Stroke

Sponsors & Collaborators

• Istanbul Medipol University Hospital

  collaborator OTHER

• Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital

  collaborator OTHER

• Başakşehir Çam & Sakura City Hospital

  collaborator OTHER_GOV

• Sisli Hamidiye Etfal Training and Research Hospital

  collaborator OTHER

• Ankara Etlik City Hospital

  collaborator OTHER_GOV

• Ankara City Hospital Bilkent

  collaborator OTHER

• Istanbul University - Cerrahpasa

  collaborator OTHER

• Trakya University

  collaborator OTHER

• Cigli Regional Training Hospital

  collaborator OTHER

• Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital

  collaborator OTHER_GOV

• İstanbul Bağcılar Training and Research Hospital

  collaborator UNKNOWN

• Istanbul Mehmet Akif Ersoy Educational and Training Hospital

  lead OTHER_GOV

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-03-03

Primary Completion

2025-08-01

Completion

2026-08-01

Countries

• Turkey (Türkiye)

Study Locations