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Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions

NCT06931574 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2025-04-17

No results posted yet for this study

Summary

The Crush technique for coronary bifurcation lesions has evolved significantly since its introduction to the literature by Colombo et al. in 2003, with several iterations, including double kissing balloon inflation. The main disadvantage of the historical Crush technique is the low success rate of the final kissing balloon inflation. An improvement came with the introduction of double kissing crush stenting aiming for the shorter protrusion and kissing balloon dilation performed before and after main branch stent implantation. The double kissing crush provides a significant reduction in major adverse cardiovascular events compared to Provisional stenting, Crush, and Culotte techniques. Recently, a novel modified mini-crush technique (controlled balloon-crush) has been introduced to the literature and is one of the most up-to-date crush techniques. The main advantage of this technique over the contemporary mini-crush technique is that the side branch can be easily rewired, and the 1:1 size non-compliant balloon can easily pass through the crushed stent structure in the ostial part of the side branch. The basic rationale of this is that the crushing of the side branch stent is done in a more controlled manner (by slowly deflation of the side branch stent balloon), and this causes less disruption of the stent cells. To date, no data compares the mid-term outcomes of double kissing crush and controlled balloon-crush stenting techniques in patients with complex coronary bifurcation lesions. Hence, this study aimed to determine the clinical results of double kissing crush and controlled balloon-crush techniques under mid-term follow-up.

Conditions

  • Coronary Arterial Disease (CAD)
  • Percutaneous Coronary Intervention (PCI)
  • Bifurcation Coronary Disease

Sponsors & Collaborators

  • Sisli Hamidiye Etfal Training and Research Hospital

    collaborator OTHER

  • Başakşehir Çam & Sakura City Hospital

    collaborator OTHER_GOV

  • Bagcilar Training and Research Hospital

    collaborator OTHER_GOV

  • Ankara Etlik City Hospital

    collaborator OTHER_GOV

  • Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital

    collaborator OTHER_GOV

  • Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital

    collaborator OTHER

  • Istanbul Medipol University Hospital

    collaborator OTHER

  • Istanbul Mehmet Akif Ersoy Educational and Training Hospital

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-01
Primary Completion
2026-11-01
Completion
2026-12-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06931574 on ClinicalTrials.gov