Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors

Summary

The AYA WELL study is a 2-arm randomized clinical trial to test the efficacy of a theory-based, mHealth weight management intervention adapted specifically for adolescent and young adult cancer survivors compared to a self-guided arm. Participants, diagnosed with cancer between ages 15-39, currently age 18-39, post-treatment at least 6 months, and who have overweight or obesity will be randomized to receive either: 1) a comprehensive mHealth weight management program (intervention) or 2) digital tools + health education + peer support (self-guided) over 12 months. Outcomes will be assessed at 3, 6, and 12 months.

Conditions

• Obesity
• Cancer
• Physical Activity
• Cancer Survivorship
• Diet

Interventions

BEHAVIORAL

AYA WELL Intervention

Behavioral weight management intervention for adolescent and young adult cancer survivors with digital tools, smartphone web app behavioral program, text messages, and expert-guided closed social networking group for peer support.

BEHAVIORAL

Self-Guided

Self-guided intervention with digital tools, periodic informational support, and moderated social networking group for peer support.

Sponsors & Collaborators

• Virginia Commonwealth University

  collaborator OTHER

• National Cancer Institute (NCI)

  collaborator NIH

• UNC Lineberger Comprehensive Cancer Center

  lead OTHER

Principal Investigators

• Carmina G. Valle, PhD, MPH · University of North Carolina, Chapel Hill

• Jessica Gokee LaRose, PhD · Virginia Commonwealth University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

39 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-10-27

Primary Completion

2028-04-30

Completion

2028-10-31

Countries

• United States

Study Locations