Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families

Summary

This trial studies how well weight management and health behavior intervention works in helping patients with hereditary breast and ovarian cancer and Lynch syndrome mutation carriers lose or maintain a healthy weight and lower their risk for cancer. Lifestyle behaviors such as physical activity, diet, and weight management may play a key role in preventing cancers and improving outcomes even in those with hereditary cancer syndromes.

Conditions

• Hereditary Breast Carcinoma
• Hereditary Ovarian Carcinoma
• Lynch Syndrome

Interventions

BEHAVIORAL

Behavioral Dietary Intervention

Record food intake

OTHER

E-mail

Receive e-mails

BEHAVIORAL

Exercise Intervention

Undergo exercise

OTHER

Health Promotion and Education

Receive text messages

OTHER

Internet-Based Intervention

Join Facebook page

OTHER

Questionnaire Administration

Ancillary studies

BEHAVIORAL

Telephone-Based Intervention

Receive telephone coaching

Sponsors & Collaborators

• National Cancer Institute (NCI)

  collaborator NIH

• M.D. Anderson Cancer Center

  lead OTHER

Principal Investigators

• Karen M Basen-Engquist · M.D. Anderson Cancer Center

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

FACTORIAL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-01-26

Primary Completion

2026-04-30

Completion

2026-04-30

Countries

• United States

Study Locations