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Effects of Overload Eccentric and Concentric Resistance Training on the Cost of Walking, Muscle-tendon and Jumping Performance in Healthy Older Individuals

NCT06838481 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2025-02-20

No results posted yet for this study

Summary

Normal aging leads to a decline in neuromuscular and mobility functions, including a 60% reduction in maximal voluntary force production, a 25% decrease in muscle volume and quality (sarcopenia), and reduced tendon stiffness by age 70. These changes impair walking speed, balance, and increase the metabolic cost of walking by \~20% in older adults compared to younger individuals. While walking training can reduce metabolic costs, no interventions have successfully addressed the 20% age-related difference. Resistance training, particularly eccentric (muscle-lengthening) training, shows promise for improving muscle strength and mass, but its effects on functional, cognitive abilities, and walking economy in older adults remain unexplored.

Conditions

  • Healthy Older Adults

Interventions

OTHER

Concentric overload resistance training

* Resistance training groups will train 2-3 times per week for 3 months using specialized TechnoGym machines. * Exercises include Concentric leg press, knee extension, and ankle plantarflexion in a progressive loading program following American College of Sports Medicine (ACSM) \& National Strength and Conditioning Association (NSCA) guidelines. * Heart rate, blood pressure, and perceived exertion will be monitored during each session.

OTHER

Eccentric overload resistance training

* Resistance training groups will train 2-3 times per week for 3 months using specialized TechnoGym machines. * Exercises include Eccentric leg press, knee extension, and ankle plantarflexion in a progressive loading program following American College of Sports Medicine (ACSM) \& National Strength and Conditioning Association (NSCA) guidelines. * Heart rate, blood pressure, and perceived exertion will be monitored during each session.

OTHER

Active Control

Walking

Sponsors & Collaborators

  • Semmelweis University

    collaborator OTHER

  • Hungarian University of Sports Science

    lead OTHER

Principal Investigators

  • Prof. DR. Tibor Hortobágyi Hortobágyi · Hungarian University of Sports Science, Department of Kinesioogy, Budapest, Hungary

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-15
Primary Completion
2025-12-15
Completion
2026-05-15

Countries

  • Hungary

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06838481 on ClinicalTrials.gov