Predictors of Bone Mineral Density in Lupus Nephritis Activity
NCT06837558 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2025-02-20
Summary
Our aim in this study is Correlation of histopathology of renal biopsy in SLE with lupus nephritis patients versus predictors of bone mineral density in active and inactive lupus nephritis
Conditions
- Bone Mineral Density and Lupus Nephritis Activity
Interventions
- DIAGNOSTIC_TEST
-
fibroblast growth factor 23
Investigations: including the different following modalititis A. Laboratory investigations include: 1. Complete blood picture, PT PC INR, RBS Kidney function tests, eGFR Urine analysis, 24 hours' protein in urine 2. Specific laboratory investigations for SLE and lupus nephritis: ANA,AntiDsDNA,C3,C4 3. Laboratory investigations of Bone mineral density predictors Ca, phosphorus, PTH, vitamin D (OH), Alkaline phosphatase, Fibroblast Growth Factor 23 (FGF 23) B. Imaging studies: 1 - Abdominal ultrasound 2- chest x-ray 3- Echocardiography (in lupus nephritis with activity form) 4- DEXA bone scan C. Invasive modality: Renal biopsy of Patients with SLE with lupus nephritis
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
Nashwa Moustafa Abdel Monem Azoz, assistant professor nephrology · Assiut university hospital internal medicine
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-04-01
- Primary Completion
- 2027-04-01
- Completion
- 2027-05-01
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