Disease Activity Biomarkers in Patients With Systemic Lupus Erythematosus
NCT05443516 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 250
Last updated 2022-07-05
Summary
The aim of this research project is to better understand the origin and clinical significance of two lupus-specific "genetic signatures" (IFN signature and plasma cell signature) in patient subgroups with well-defined clinical characteristics. Our aim is to correlate these genetic signatures with cell activation profiles and the production of specific cytokines in different populations from whole blood and in short-term cultures of these circulating cells.
Conditions
Sponsors & Collaborators
-
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
lead OTHER
Principal Investigators
-
Frédéric Houssiau, Pr · Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-06-16
- Primary Completion
- 2022-12-31
- Completion
- 2032-12-31
Countries
- Belgium
Study Locations
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