Radiotherapy of Head and Neck Cancer With SIB
NCT06831903 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 750
Last updated 2025-02-18
Summary
Title: Simultaneous Integrated Boost in Primary and Adjuvant Therapy of Head and Neck Tumors: Quality Control Registry Prospective Longitudinal Observational Study
Short Title: Radiotherapy for Head and Neck Tumors with SIB
Objective: To evaluate the efficacy and safety of definitive and adjuvant radio(chemo)therapy with simultaneous integrated boost (SIB) in patients with head and neck cancers. The study aims to assess local and regional control, overall survival, metastasis-free survival, therapy-related toxicities, and quality of life.
Study Design: A prospective, longitudinal, non-interventional registry study documenting real-world outcomes and quality measures of therapy applied according to existing clinical guidelines.
Conditions
- Quality of Life (QOL)
- Head and Neck Cancer
- Radiotherapy Side Effect
- Radiotherapy, Conformal (IMRT)
Sponsors & Collaborators
-
Wuerzburg University Hospital
lead OTHER
Principal Investigators
-
Victor Lewitzki, MD, PhD · University Clinic of Wuerzburg, Department of Radiation Oncology
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-05-21
- Primary Completion
- 2034-10-01
- Completion
- 2039-10-01
Countries
- Germany
Study Locations
More Related Trials
-
Stereotactic Radiosurgery in Patients With Head and Neck Region Tumours
NCT06472570 ·Status: RECRUITING ·Phase: NA
-
Phase II Study of Adjuvant SIB Radiotherapy Following Narrow-Margin Hepatectomy in Patients With HCC.
NCT06205472 ·Status: RECRUITING ·Phase: PHASE2
-
Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC
NCT06137274 ·Status: RECRUITING ·Phase: PHASE2
-
A Feasibility Study On Continuous Adaptive [18f]Fdg-Pet-Guided Radiotherapy For Head and Neck Cancer
NCT01208883 ·Status: COMPLETED ·Phase: PHASE1
-
Surgery With or Without Adjuvant Stereotactic Body Radiotherapy
NCT02516969 ·Status: COMPLETED ·Phase: NA
-
Individualized Response-adaptive Radiation Dose Prescription in HNC Based on MRI
NCT05160714 ·Status: UNKNOWN ·Phase: PHASE1
-
Multimodality- Adapted Dose Modification in Head and Neck Cancer Radiation Therapy 
NCT04933357 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Intensity-modulated Radiotherapy (IMRT) With Simultaneous Integrated Boost (SIB) for Inoperable Non-small-cell Lung Cancer
NCT02841228 ·Status: UNKNOWN ·Phase: PHASE2
-
Combination of SBRT and Immunotherapy in Small Hepatocellular Carcinoma (HSBRT2402)
NCT06313190 ·Status: RECRUITING ·Phase: PHASE2
-
Safety and Efficacy of SBRT in the Reirradiation for Ultra-central Thoracic Malignant Tumors
NCT05189054 ·Status: RECRUITING
-
Phase II Study of Whole or Partial Parotid Sparing Intensity Modulated Radiotherapy in Patients With Head and Neck Cancers
NCT02068313 ·Status: UNKNOWN
-
Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful Non-Spine Bone Metastases
NCT06391242 ·Status: RECRUITING ·Phase: PHASE3
-
Assessment of Different Therapeutic Strategies in Patients With Head and Neck Neoplasms Treated With Radiotherapy
NCT06773039 ·Status: RECRUITING
-
A Feasibility Study of Adaptive Intensity-Modulated Radiation Therapy
NCT00608751 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Do Markers of Systemic Inflammatory Response and Tumor Metabolism Indicate Radioresistance in Head and Neck Cancer?
NCT05217212 ·Status: RECRUITING
-
Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection
NCT06189183 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Efficacy and Safety of SBRT Combined With Atezolizumab Plus Bevacizumab vs Atezolizumab Plus Bevacizumab in Treating Unresectable Advance Hepatocellular Carcinoma.
NCT06244446 ·Status: NOT_YET_RECRUITING
-
INRT-AIR: A Prospective Phase II Study of Involved Nodal Radiation Therapy
NCT03953976 ·Status: COMPLETED ·Phase: PHASE2
-
Hypofractionated Radiotherapy in Breast Cancer
NCT03167359 ·Status: COMPLETED ·Phase: NA
-
Dose De-escalation to the Elective Nodal Sites in Head and Neck Cancer
NCT01812486 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer.
NCT01341535 ·Status: COMPLETED ·Phase: PHASE2
-
Stereotactic Body Radiotherapy for Head and Neck Tumors
NCT01344356 ·Status: COMPLETED ·Phase: PHASE4
-
Stereotactic Multiple Fraction Radiotherapy for Non-spine Bone Metastases
NCT05406063 ·Status: RECRUITING ·Phase: NA
-
Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck
NCT01287390 ·Status: COMPLETED ·Phase: PHASE2
-
SBRT-based PArtial Tumor Irradiation of HYpoxic Segment
NCT04168320 ·Status: TERMINATED ·Phase: PHASE1