Do Markers of Systemic Inflammatory Response and Tumor Metabolism Indicate Radioresistance in Head and Neck Cancer?
NCT05217212 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2023-10-10
Summary
The aim of the study is to prospectively evaluate whether markers of a patient's systemic inflammatory response in addition to FDG-PET/CT metabolic parameters of the primary tumor or of nodal metastases can predict radioresistance and survival before primary radiochemotherapy in advanced head and neck cancer patients.
Conditions
Interventions
- RADIATION
-
Radiochemotherapy
Primary radiotherapy of the primary tumor and nodal basin with curative intent with or without concomitant chemotherapy with cisplatin, carboplatin, or cetuximab weekly.
Sponsors & Collaborators
-
Universität Luzern
collaborator OTHER -
Luzerner Kantonsspital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-01-01
- Primary Completion
- 2024-12-31
- Completion
- 2025-12-31
Countries
- Switzerland
Study Locations
More Related Trials
-
Stereotactic Radiosurgery in Patients With Head and Neck Region Tumours
NCT06472570 ·Status: RECRUITING ·Phase: NA
-
A Feasibility Study On Continuous Adaptive [18f]Fdg-Pet-Guided Radiotherapy For Head and Neck Cancer
NCT01208883 ·Status: COMPLETED ·Phase: PHASE1
-
Tumor Hypoxia of Head-and-neck Cancer Underwent Radiation Therapy Measured With F-18-FMISO
NCT00180180 ·Status: COMPLETED
-
Effectiveness of Adjuvant Radiotherapy in Small Oropharyngeal Squamous Cell Cancer and Single Lymph Node Metastasis.
NCT00964977 ·Status: COMPLETED ·Phase: PHASE3
-
Immunotherapy Clearance and Phenotype of Circulating Tumor Cells in Lung and Head and Neck Cancers
NCT05091190 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
A Feasibility Study on Adaptive 18F-FDG-guided Radiotherapy for Recurrent and Second Primary Head and Neck Cancer in the Previously Irradiated Territory.
NCT01427010 ·Status: COMPLETED ·Phase: NA
-
Tumor Response in Hypofractionated Radiotherapy
NCT02854449 ·Status: UNKNOWN
-
Proton Boost for Locally Advanced HEAD AND NECK TUMORS
NCT03183271 ·Status: COMPLETED ·Phase: NA
-
Functional Imaging in HNC Undergoing Chemoradiation
NCT00837980 ·Status: UNKNOWN
-
Impact of Selective Radiation Dose Escalation and Tumour Hypoxia Status on Locoregional Tumour Control After Radiochemotherapy of HNT
NCT01212354 ·Status: UNKNOWN ·Phase: PHASE3
-
Preventive Physical Activity Intervention in Head and Neck Cancer
NCT05432297 ·Status: RECRUITING ·Phase: NA
-
Prospective Study on Factors Predicting Chemo-Radiotherapy Induced Pulmonary and Esophageal Injury
NCT00631839 ·Status: UNKNOWN
-
Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers
NCT04242459 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Assessment of Different Therapeutic Strategies in Patients With Head and Neck Neoplasms Treated With Radiotherapy
NCT06773039 ·Status: RECRUITING
-
Detection of Circulating Biomarkers of Immunogenic Cell Death
NCT02921854 ·Status: COMPLETED ·Phase: NA
-
Predictive Modelling for Patient Stratification According to Treatment-related Toxicity and Survival After Chemoradiation for Head and Neck Cancer
NCT02103010 ·Status: COMPLETED
-
Prediction of Outcome After Chemoradiotherapy for Head and Neck Cancer Using Functional Imaging and Tumor Biology
NCT01829646 ·Status: RECRUITING ·Phase: NA
-
FMISO-based Adaptive Radiotherapy for Head and Neck Cancer
NCT05348486 ·Status: RECRUITING ·Phase: NA
-
Radiotherapy Treatments for Neoplasms in the Head and Neck Region
NCT06335342 ·Status: RECRUITING
-
Quality of Life Assessment of Radiotherapy in Recurrent Head and Neck Cancer
NCT05850663 ·Status: WITHDRAWN ·Phase: NA
-
Radiofrequency Ablation Combined With Chemotherapy for Pulmonary Tumors
NCT01105182 ·Status: UNKNOWN
-
Stereotactic Radiosurgery (SRS) for Spine Metastases
NCT00593320 ·Status: TERMINATED ·Phase: NA
-
Assessment of Early Radiation Oncology Involvement Alongside Standard Oncologic Care in the Managemet
NCT05351294 ·Status: SUSPENDED ·Phase: PHASE3
-
Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer
NCT02379039 ·Status: COMPLETED
-
SBRT + Immunomodulating Systemic Therapy for Inoperable, Recurrent H&N
NCT03402737 ·Status: TERMINATED ·Phase: NA