Stereotactic Multiple Fraction Radiotherapy for Non-spine Bone Metastases
NCT05406063 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 162
Last updated 2025-05-22
Summary
To investigate, whether multi-fraction stereotactic body radiation therapy (SBRT) within 3 treatment fractions is non-inferior to the current standard of care of 5 fraction SBRT regarding pain response at 3 months after radiotherapy.
Conditions
- Radiation Therapy
- Bone Metastases
- Pain
Interventions
- RADIATION
-
SBRT
Stereotactic multiple fraction radiotherapy
Sponsors & Collaborators
-
Krebsforschung Schweiz, Bern, Switzerland
collaborator OTHER -
Kantonsspital Winterthur KSW
lead OTHER
Principal Investigators
-
Robert Foerster, MD · Kantonsspital Winterthur KSW
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-01
- Primary Completion
- 2025-05-31
- Completion
- 2026-05-31
Countries
- Switzerland
Study Locations
More Related Trials
-
Stereotactic Body Radiotherapy (SBRT) for Spinal/Para-Spinal Metastases (Spine SBRT)
NCT01290562 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial Comparing Dose-intensified SBRT With Conventional Radiation Therapy for Spinal Metastases
NCT02800551 ·Status: COMPLETED ·Phase: PHASE2
-
A Dose-escalation Trial of Stereotactic Ablative Body Radiotherapy for Non-spine Bone & Lymph Node Oligometastates
NCT03486431 ·Status: COMPLETED ·Phase: NA
-
Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery
NCT02527304 ·Status: COMPLETED ·Phase: NA
-
A Prospective Randomized Trial of High Dose Versus Standard Dose Stereotactic Radiotherapy for Pain Control in Patients With Bone Metastases
NCT04063254 ·Status: UNKNOWN ·Phase: PHASE2
-
Randomized Study of Stereotactic Body Radiotherapy vs. Conventional Radiation for Spine Metastasis
NCT01525745 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases
NCT06065449 ·Status: RECRUITING ·Phase: PHASE3
-
Preoperative Stereotactic Radiotherapy for Treatment of Spinal Metastases
NCT07135817 ·Status: RECRUITING ·Phase: NA
-
Evaluate the Efficacy of Radiofrequency Ablation/Vertebroplasty with or Without SBRT for Treating Painful Spinal Vertebral Metastases
NCT06756087 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Reduction of Pain Symptoms With Stereotactic Radiotherapy on Bone Metastases
NCT03597984 ·Status: UNKNOWN ·Phase: NA
-
Randomized Trial on Same-day SBRT and Surgical Stabilization for Symptomatic Spinal Metastases
NCT05575323 ·Status: RECRUITING ·Phase: NA
-
A Single-center Observational Clinical Trial of Stereotactic Radiotherapy on Metastatic Spinal Tumors Using TomoTherapy
NCT05808998 ·Status: UNKNOWN
-
Bony M - Stereotactic Ablative Radiotherapy (SABR) of Bony Metastases in Patients With Oligometastatic Disease
NCT05101824 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Stereotactic Body Radiotherapy for Spine Tumors
NCT01347307 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Body Radiation Therapy and Vertebroplasty in Treating Patients With Localized Spinal Metastasis
NCT00855803 ·Status: COMPLETED ·Phase: PHASE2
-
Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer
NCT03862911 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Prospective Evaluation of Stereotactic Body Radiotherapy for Metastatic Prostate Cancer
NCT02206724 ·Status: WITHDRAWN ·Phase: NA
-
Single-isocenter SBRT vs. Multiple-isocenter SBRT for Multiple Extracranial Metastases
NCT06230666 ·Status: RECRUITING ·Phase: NA
-
Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone
NCT02880319 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Stereotactic Body Radiotherapy for Unresectable Pancreatic Cancer
NCT01346410 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Body Radiation Therapy (SBRT) for Tumors Near the Spinal Cord
NCT00631670 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Radiosurgery (SRS) for Spine Metastases
NCT00593320 ·Status: TERMINATED ·Phase: NA
-
Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial
NCT06563388 ·Status: RECRUITING ·Phase: PHASE3
-
Study Comparing Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy (CRT) for Spinal Metastases
NCT02512965 ·Status: COMPLETED ·Phase: NA
-
A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy
NCT06859801 ·Status: RECRUITING