MedTrace Logo

Impact of Collagen Supplements on Dermal Collagen in Plastic and Bariatric Surgery Patients

NCT06787924 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 102

Last updated 2026-02-17

No results posted yet for this study

Summary

This study aims to evaluate the effects of oral collagen supplementation on dermal collagen content in skin biopsies of patients undergoing abdominoplasty. Using a randomized controlled trial (RCT) design, participants from metabolic bariatric surgery (MBS) and plastic surgery groups will receive either collagen supplements or a placebo for several weeks. Biopsies will be collected pre-intervention and during surgery to compare collagen levels between groups and to baseline. The primary objective is to determine if collagen supplementation significantly enhances dermal collagen deposition compared to placebo and initial levels.

Conditions

  • Bariatric Surgery
  • Abdominoplasty
  • Collagen Synthesis
  • Skin Physiology
  • Randomized Controlled Trial
  • Tissue Remodeling

Interventions

DIETARY_SUPPLEMENT

Collagen hydrolyzed peptides

bovine collagen peptides

DIETARY_SUPPLEMENT

Starch

Starch placebo

Sponsors & Collaborators

  • General Committee of Teaching Hospitals and Institutes, Egypt

    lead OTHER_GOV

Principal Investigators

  • Mohamed Hany Ashour, professor, MD · Alexandria University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-04-15
Primary Completion
2025-10-31
Completion
2025-12-15

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06787924 on ClinicalTrials.gov