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The Impact of De-implementing Urine Dipsticks for Diagnosis of UTIs in Hospitals

NCT06750666 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 480000

Last updated 2025-10-01

No results posted yet for this study

Summary

The goal of this interrupted time-series analysis is to evaluate the impact of the de-implementation of urine dipsticks as a diagnostic tool for urinary tract infections (UTIs) in hospitalized patients in the North Denmark Region. The main question it aims to answer is:

How does de-implementation of urine dipsticks affect the diagnosis and management of UTIs and related disorders?

Specifically, does it change the following parameters:

* Number and severity of UTI infections (lower and upper UTI, non-severe and severe)
* Antibiotic prescription (overall, antibiotic classes, administration routes, duration, dosages)
* Number of urine cultures and number of positive urine cultures
* Risks of admission to intensive care units and 30-day mortality
* Risk of drug toxicity
* Length of hospital stay
* Risk of admission to intensive care unit
* 30-day risk of readmission after discharge
* 6-month risks of Clostridioides difficile enterocolitis and de novo antimicrobial resistance in cultures obtained during routine clinical care.

Researchers hypothesize that de-implementing urine dipsticks will lead to a reduced frequency of diagnosed cystitis, reduced antibiotic use, and fewer urine cultures without negatively affecting patient mortality or readmission risk.

Researchers will compare the outcomes before and after the discontinuation of urine dipsticks across hospitals in the North Denmark Region. Furthermore, results will be compared to another Danish administrative healthcare region where dipsticks are still in use as well as urine culture data from the primary sector in the North Denmark Region.

Since this is a registry-based observational study utilizing data from the electronic patient record system in the North Denmark Region, no direct contact will be made with participants.

Conditions

  • Urinary Tract Infections
  • Diagnostic Techniques and Procedures
  • Point-of-Care Testing
  • Anti-Bacterial Agents
  • Registry
  • Clinical Decision-making
  • Urinalysis

Interventions

DIAGNOSTIC_TEST

De-implementation of Urinary Dipsticks

In August 2023 / February 2024, urinary dipsticks were de-implemented in hospitals across the North Denmark Region. Using registry-based data, the investigators aim to evaluate the clinical impact of this decision.

OTHER

Usual practice with no intervention

In hospitals within the Central Denmark Region and in the primary care sector, urinary dipsticks have not been de-implemented and remain in use. Registry-based data from these settings will serve as a control.

Sponsors & Collaborators

  • Jacob Bodilsen

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-31
Primary Completion
2026-06-30
Completion
2026-12-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06750666 on ClinicalTrials.gov