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Relationship Between Pulse Pressure and Stroke Volume in the Critically Ill Patients: The ANDROMEDA-PEGASUS Study

NCT06737614 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1500

Last updated 2025-05-29

No results posted yet for this study

Summary

The goal of this study is to assess the predictive capacity of pulse pressure to estimate stroke volume, as assessed by bedside echocardiography in critically ill patients.

We hypothesize that pulse pressure will be able to adequately detect low values of stroke volume, and to track changes of stroke volume during commonly used dynamic cardiovascular interventions.

Pulse pressure transduced from an arterial line will be measured simultaneously with left ventricular outflow tract velocity time integral in a broad range of critically ill patients. Ancillary clinical, hemodynamic and echocardiographic data will also be registered.

Conditions

  • Critical Illness

Sponsors & Collaborators

  • Erasmus Medical Center

    collaborator OTHER

  • Fundacion Clinica Valle del Lili

    collaborator OTHER

  • Hospital do Coracao

    collaborator OTHER

  • Pontificia Universidad Catolica de Chile

    lead OTHER

Principal Investigators

  • Eduardo Kattan, MD, PhD · Assistant Professor

  • Glenn Hernandez, MD, PhD · Full Professor

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-01
Primary Completion
2025-10-30
Completion
2026-01-30

Countries

  • Brazil
  • Chile
  • Colombia

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06737614 on ClinicalTrials.gov