Translocator Protein PET/CT in Various TSPO-Related Disease
NCT06725719 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2025-02-11
Summary
To evaluate the potential usefulness of 18F-DPA714/FDPA positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various TSPO-related disease patients.
Conditions
- Neuroinflammation
- Stroke
- Neurodegenerative Diseases
Interventions
- DIAGNOSTIC_TEST
-
18F-DPA714/FDPA
Each subject receive a single intravenous injection of 18F-DPA714/FDPA, and undergo PET/CT or MRI imaging within the specificed time.
Sponsors & Collaborators
-
Tianjin Medical University General Hospital
collaborator OTHER -
Tianjin Medical University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-11-01
- Primary Completion
- 2027-12-01
- Completion
- 2027-12-01
Countries
- China
Study Locations
More Related Trials
-
Targeted Translocator Protein PET Imaging Evaluate Neuroinflammation of the Chronic Pain Patients
NCT06701734 ·Status: NOT_YET_RECRUITING
-
2-(1-{6-[(2-[F-18]Fluoroethyl) (Methyl)Amino]-2-naphthyl} Ethylidene) Malononitrile-PET for in Vivo Diagnose of Tauopathy in Unclassified Parkinsonism
NCT02214862 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
TSPO-PET/MRI in Surveillance of Neuroinflammation in the Central Nervous System
NCT06467773 ·Status: RECRUITING
-
Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease
NCT06092125 ·Status: RECRUITING
-
Hydroxyephedrine PET/CT in Sympathetic Nervous System Disease
NCT06951984 ·Status: RECRUITING
-
PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand
NCT03958630 ·Status: TERMINATED ·Phase: PHASE1
-
[18F]NIDF PET Imaging in Tau-related Diseases
NCT07306598 ·Status: RECRUITING
-
TSPO PET in the Evaluation of Neuroinflammation in Patients with Multiple System Atrophy
NCT06890390 ·Status: RECRUITING
-
Molecular Imaging of NET Using [C-11]MRB-PET in MS
NCT03207464 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
[18F]MC225-PET in Neurodegenerative Disease
NCT05853471 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Translocator Protein and Inflammation After Traumatic Brain Injury
NCT01547780 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
F 18 T807 Tau PET Imaging in Dominantly Inherited Alzheimer's Network (DIAN Project)
NCT02414178 ·Status: ENROLLING_BY_INVITATION
-
Tau Protein and SV2a Imaging in Patients With Tau Protein-related Diseases
NCT05260151 ·Status: UNKNOWN
-
[18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy Subjects
NCT05564429 ·Status: TERMINATED ·Phase: PHASE1
-
Multimodel Magnetic Resonance Imaging (MRI)of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
NCT02836327 ·Status: UNKNOWN
-
FDDNP Protocol for Visualizing Brain Proteinopathies to Assist in the Diagnosis of Persons With Suspected CTE and AD
NCT04311281 ·Status: WITHDRAWN
-
Clinical Study of [18F] PM-PBB3 PET Imaging of Tau Protein in Neurodegenerative Diseases
NCT06344845 ·Status: RECRUITING ·Phase: NA
-
18F-DTBZ PET and Multi-modal MRI in the Patients With Vascular Parkinsonism
NCT02195154 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Clinical Decision Support System for Brain Metastasis Using Brain MR Images
NCT05573815 ·Status: UNKNOWN ·Phase: NA
-
PET Tau - Neurodegenerative Disease Imaging
NCT03143374 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects
NCT02103894 ·Status: COMPLETED ·Phase: PHASE1
-
PET Imaging of the Translocator Proteine Ligands (TSPO) With [18 F] DPA-714 Biomarker of NeuroInflammation in Cognitive Decline (NIDECO)
NCT02062099 ·Status: COMPLETED ·Phase: PHASE1
-
Longitudinal Investigation of I2BS in PD
NCT05516719 ·Status: RECRUITING
-
A Study of Imaging in Demyelinating Diseases
NCT05805839 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Contrast-enhanced Magnetic Resonance Imaging With Polysaccharide Superparamagnetic Iron Oxide Nanoparticle
NCT06010537 ·Status: COMPLETED ·Phase: EARLY_PHASE1