Immunomodulatory Therapy & VSA
NCT06696807 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 71
Last updated 2024-11-20
Summary
Vasospastic angina (VSA) is caused by brief spasms of the main coronary artery and its major branches, resulting in varying degrees of luminal occlusion. Although vasodilator therapy is widely used and significantly alleviates VSA symptoms, it has not led to notable improvements in the prognosis of patients with VSA. Recent studies have suggested that inflammation plays a crucial role in VSA. This study aimed to evaluate the potential effectiveness of immunomodulatory therapy for improving patient prognosis.
Conditions
- Vasospastic Angina
Interventions
- DRUG
-
glucocorticosteroids and/or intravenous immunoglobulin
methylprednisolone: 20-200mg/day intravenous immunoglobulin: 5-20 g/day
Sponsors & Collaborators
-
Dao Wen Wang
lead OTHER
Eligibility
- Min Age
- 15 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-10-01
- Primary Completion
- 2024-04-01
- Completion
- 2024-05-01
Countries
- China
Study Locations
More Related Trials
-
Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina
NCT02529189 ·Status: COMPLETED ·Phase: PHASE2
-
The Effects of Inorganic Nitrate on Cardiac Muscle in Angina
NCT02078921 ·Status: COMPLETED ·Phase: PHASE2
-
Effectiveness of a Combination of Trimetazidine With One Hemodynamic Agent in Patients Recently Diagnosed With Stable Angina and Still Symptomatic Despite First Line Hemodynamic Therapy
NCT06298045 ·Status: RECRUITING
-
Local Antioxidant Therapy Vasoconstriction Effects in Different Races
NCT03684213 ·Status: COMPLETED ·Phase: PHASE1
-
Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation
NCT00204984 ·Status: COMPLETED ·Phase: NA
-
Prevention and Comparison of Different Forms of Administration of Nitrates in the Risk of Radial Spasm During Coronary Angiography.
NCT02258620 ·Status: COMPLETED ·Phase: NA
-
Real-world Use and Prognosis of Beta Blocker in Patients With Acute Coronary Syndrome in the Central China
NCT03116854 ·Status: COMPLETED
-
The Link Between the Clinical Resting Heart Rate and Sympathetic Overactivation
NCT02315313 ·Status: UNKNOWN
-
The Prevalence of Coronary Spasm in Hypertensive Patients Treated With Antihypertensive Medication
NCT01882790 ·Status: COMPLETED
-
Extracorporeal Shock Wave Therapy for the Treatment of Ischemic Heart Disease
NCT01241968 ·Status: UNKNOWN ·Phase: PHASE2
-
Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCA
NCT06948201 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity
NCT01919177 ·Status: COMPLETED ·Phase: PHASE2
-
The Effect of Nebivolol in Hypertensive Patients With Coronary Arterial Spasm
NCT03930433 ·Status: COMPLETED ·Phase: PHASE4
-
A Prospective Study to Evaluate the Effect of Chronic Nitrate Therapy on Vasodilation Function in Coronary Heart Disease
NCT01430780 ·Status: UNKNOWN
-
Effect of Isosorbide Mononitrate on Hypertension to Improve Left Ventricular Hypertrophy, Fibrosis and Myocardial Function
NCT01961453 ·Status: WITHDRAWN ·Phase: PHASE2
-
Effects of Dietary Nitrate Intake on Cardiovascular Performance in Response to Hand Grip Test in Bodybuilders
NCT05835401 ·Status: COMPLETED ·Phase: NA
-
Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension
NCT02425566 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
The Prognostic Role of Indices of Sympathetic Nervous System Overdrive in MINOCA
NCT04681612 ·Status: UNKNOWN
-
Estimation of the Long Term Effectiveness of Routine Use of Cardiac Shock Wave Therapy
NCT01631409 ·Status: WITHDRAWN
-
Pilot Study On The Role Of Nitric Oxide In Alpha 1-Adrenergic Vasoreactivity
NCT00240058 ·Status: COMPLETED ·Phase: NA
-
Dietary Nitrate and Nitrite to Increase Nitric Oxide in Patients With Coronary Artery Disease
NCT00069654 ·Status: COMPLETED ·Phase: PHASE2
-
Role of Endothelin-1 in Flow-mediated Dilatation
NCT02086253 ·Status: COMPLETED ·Phase: NA
-
Nitroglycerin as Spasmolytic Regimen for RAS Prevention in Radial Center
NCT03889470 ·Status: UNKNOWN ·Phase: PHASE4
-
Vascular Response to Isoproterenol and β2 Adrenergic Receptor Polymorphisms
NCT00226551 ·Status: COMPLETED ·Phase: NA
-
Sympathetic Regulation of Large Artery Stiffness in Humans With ISH
NCT04423627 ·Status: COMPLETED ·Phase: EARLY_PHASE1