MedTrace Logo

Fibrinolysis Resistance in Infection and Trauma

NCT06680180 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2024-11-08

No results posted yet for this study

Summary

Blood coagulation disorders are often seen in critically ill patients e.g. with severe infection or following extensive injury, that can lead to life threatening events as a result of excessive blood clot formation leading to organ failure. This study aims to use Viscoelastic Testing (VET) technology to detect patients at risk of excessive blood blot formation at the bedside, test new blood coagulation drugs, and guide life-saving use of blood modifying treatments.

Conditions

  • Sepsis and Septic Shock
  • Trauma

Interventions

DIAGNOSTIC_TEST

Viscoelastometric assessment of fibrinolysis

Viscoelastometric assessment of whole blood fibrinolysis using supplemental tissue plasminogen activator (tPA) and other agents ex vivo to influence fibrinolysis capacity.

Sponsors & Collaborators

  • Liverpool Hospital, South Western Sydney Local Health District

    collaborator UNKNOWN

  • The Canberra Hospital

    collaborator OTHER

  • Royal North Shore Hospital

    collaborator OTHER

  • Macquarie University, Australia

    collaborator OTHER

  • Anders Aneman

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-06-01
Primary Completion
2025-12-31
Completion
2026-06-01

Countries

  • Australia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06680180 on ClinicalTrials.gov