Metabolic and Cognitive Parameters Following Partial Sleep Deprivation

Summary

The purpose of this study is to determine whether partial sleep deprivation, as compared with normal sleep, influences certain metabolic and cognitive parameters, related to food intake, hunger and memory functions, when participants are shielded from external time cues.

Conditions

• Sleep Deprivation
• Sleep

Interventions

BEHAVIORAL

Portion Size Task

Participants are given a computer program that gives them the opportunity to choose the portions of a variety of food items that they would ideally like to consume

PROCEDURE

Blood sample

In the morning following partial sleep deprivation or normal sleep, a blood sample will be taken to assess the level of metabolism-linked and neurodegenerative-linked molecules, as well as to assay blood serum and plasma for the presence of hormones involved in hunger such as ghrelin

PROCEDURE

Interference task

30-minute interference task

BEHAVIORAL

Memory tasks

Participants will be allowed to learn a procedural memory task before going to bed. Participants will be retested in the morning to assess their change in performance. Other memory tests will also be given to assess the working memory performance in the morning following the intervention.

BEHAVIORAL

Intake task

After a normal night of sleep or partial sleep deprivation, participants are presented with an ad libitum meal choice and can select the amount to ingest during a limited time window. Amount and selection will be recorded

BEHAVIORAL

Working memory function task

Participants will be evaluated on their working memory performance in the morning following either nighttime intervention (NS or PSD)

Sponsors & Collaborators

• Uppsala University

  lead OTHER

Principal Investigators

• Christian Benedict, PhD · Department of Neuroscience, Uppsala University

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

20 Years

Max Age

28 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2013-04-30

Primary Completion

2015-03-31

Completion

2015-03-31

Countries

• Sweden

Study Locations