Perioperative Tislelizumab for Resectable II-IIIB(N2) KRAS-mutated Nonsquamous Non-small Cell Lung Cancer
NCT06659042 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2025-05-18
Summary
The primary objective of the perioperative study is to evaluate pathological complete response in resectable II-IIIB(N2) KRAS-mutated nonsquamous non-small cell lung cancer participants receiving tislelizumab plus platinum-based doublet chemotherapy.
Conditions
- Lung Cancer, Non-Small Cell
Interventions
- DRUG
-
Tislelizumab
administered via Intravenous (IV) injection
- DRUG
-
administered via IV infusion
- DRUG
-
administered via IV infusion
- DRUG
-
Pemetrexed Disodium
administered via IV infusion
Sponsors & Collaborators
-
Shanghai Chest Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-11-20
- Primary Completion
- 2025-11-20
- Completion
- 2027-11-20
Countries
- China
Study Locations
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