Real-World Assessment of Therapeutic Strategies and Survival Outcomes Following First-Line Tislelizumab Therapy in Advanced Non-Small Cell Lung Cancer
NCT06962449 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2025-05-08
Summary
This study is an observational study evaluating the treatment patterns and clinical outcomes after progression on first-line Tislelizumab treatment in advanced NSCLC. Based on the inclusion and exclusion criteria, patients with advanced NSCLC who received first-line Tislelizumab treatment and progressed will be retrospectively screened and collected from January 1, 2020, to the study initiation date, and followed up for observation.
Conditions
- Non-Small-Cell Lung Cancer
- Non-Small-Cell Lung Cancer Stage IV
Sponsors & Collaborators
-
Shanghai Chest Hospital
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-08-16
- Primary Completion
- 2025-06-30
- Completion
- 2026-12-31
Countries
- China
Study Locations
More Related Trials
-
Tislelizumab Combined With Sitravatinib as Consolidation Treatment Following Concurrent Chemoradiation in Patients With Locally Advanced, Unresectable NSCLC
NCT05176925 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy, Safety, and Pharmacodynamics of Tislelizumab Monotherapy and Multiple Tislelizumab-based Immunotherapy Combinations in Participants With Resectable Non-Small Cell Lung Cancer
NCT05577702 ·Status: COMPLETED ·Phase: PHASE2
-
The Clinical Characteristics and Efficacy of Immunotherapy in First-line PD-L1-negative Advanced NSCLC Patients
NCT06496009 ·Status: NOT_YET_RECRUITING
-
A Study of Tislelizumab in Combination With Chemotherapy Versus Chemotherapy in Advanced Lung Cancer
NCT03594747 ·Status: COMPLETED ·Phase: PHASE3
-
An Exploratory Study of Tislelizumab in Combination with Chemotherapy in Immuno-experienced Patients with EGFR/ALK/ROS1-negative Advanced NSCLC in the Second-line Setting
NCT06749886 ·Status: RECRUITING ·Phase: PHASE2
-
Tislelizumab in Combination with Chemotherapy ± Radiotherapy for Extensive-Stage Oligometastatic Small Cell Lung Cancer.
NCT06851819 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study Evaluating the Efficacy and Safety of Tislelizumab Versus Chemotherapy in Advanced Non-Squamous Non-small Cell Lung Cancer
NCT03663205 ·Status: COMPLETED ·Phase: PHASE3
-
Tislelizumab Plus Chemotherapy as First-Line Treatment for Advanced Squamous NSCLC With Brain Metastases
NCT05207904 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Study on Using TCR to Predict the Effect of Tislelizumab + Chemotherapy in the First-line Treatment of ES-SCLC
NCT07244016 ·Status: RECRUITING
-
Tislelizumab Combined With Chemotherapy and Relayed Radiotherapy in First-line Treatment of ES-SCLC
NCT06838208 ·Status: RECRUITING ·Phase: PHASE2
-
Perioperative Tislelizumab for Resectable II-IIIB(N2) KRAS-mutated Nonsquamous Non-small Cell Lung Cancer
NCT06659042 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of TQB2450 Injection Plus Chemotherapy Followed by TQB2450 Plus Anlotinib Versus Tislelizumab Plus Chemotherapy Followed by Tislelizumab in the Treatment of First-line Non-squamous Non-small Cell Lung Cancer(NSCLC).
NCT05346952 ·Status: UNKNOWN ·Phase: PHASE3
-
Stereotactic Body Radiotherapy Followed by Tislelizumab Plus Platinum-based Chemotherapy Versus Tislelizumab Plus Platinum-based Chemotherapy as Neoadjuvant Therapy in Patients With Resectable Stage Ⅱ-Ⅲ Non-small Cell Lung Cancer: A Phase Ⅲ, Randomized, Multicenter, Prospective Study
NCT06598527 ·Status: RECRUITING ·Phase: PHASE3
-
An Open-label, Single-arm Clinical Study of Stapokibart Injection in Combination with Tislelizumab Injection in Patients with Non-Small Cell Lung Cancer
NCT06883552 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Real World Study of Platinum Containing Dual Drug Chemotherapy Followed by Large Fractionated Radiotherapy Combined withTislelizumab in Stage IIIB/C-IV Non-small Cell Lung Cancer Patient
NCT07198217 ·Status: RECRUITING ·Phase: PHASE2
-
Tislelizumab Combined With Chemotherapy With or Without Bevacizumab in TKI-Resistant EGFR-Mutated Non-squamous NSCLC
NCT04405674 ·Status: UNKNOWN ·Phase: PHASE2
-
Tislelizumab Combined With sCRT in Stage IIIB/C-IV Non-Squamous Non-Small Cell Lung Cancer:A Prospective, Single-Arm, Phase II Study
NCT07085182 ·Status: RECRUITING ·Phase: PHASE2
-
Predictive Biomarker for Efficacy and Safety of Combination of Chemotherapy and Tislelizumab in NSCLC
NCT05244837 ·Status: UNKNOWN ·Phase: PHASE2
-
SBRT Followed by Neoadjuvant Immunochemotherapy in Resectable Stage II to III Non-small Cell Lung Cancer
NCT05319574 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Tislelizumab Plus Chemotherapy With Response-Adapted Radiotherapy for de Novo Metastatic Nasopharyngeal Carcinoma: A Prospective, Phase II Trial
NCT07248696 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Immunotherapy and Chemotherapy in Unresectable Recurrent Loco-regionally Advanced Nasopharyngeal Carcinoma
NCT04921995 ·Status: UNKNOWN ·Phase: PHASE2
-
Integrating Surgery and Radiotherapy Following Tislelizumab-based Conversion Therapy in N3-Stage III NSCLC
NCT06908733 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Tislelizumab Consolidation Therapy After Radiotherapy or Sequential Chemoradiation in Locally Advanced NSCLC Patients
NCT05758116 ·Status: RECRUITING ·Phase: PHASE2
-
Low-Dose Radiation + SBRT + Tislelizumab Plus Platinum-based Chemotherapy in Stage ⅡA-ⅢB Non-small Cell Lung Cancer
NCT06877299 ·Status: RECRUITING ·Phase: PHASE2
-
Clinical Randomized Study of Concurrent Chemo-radiotherapy vs Radiotherapy Alone to Local-advanced Small Cell Lung Cancer (SCLC)
NCT01745445 ·Status: UNKNOWN ·Phase: PHASE2