Impact of the COVID-19 Pandemic on Oncologic Outcomes in Colorectal Cancer

NCT06638957 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 14951

Last updated 2024-10-15

No results posted yet for this study

Summary

The goal of this observational study is to assess the impact of the COVID-19 pandemic on colorectal cancer (CRC) outcomes, particularly focusing on stage distribution and recurrence-free survival in patients undergoing surgery at eight tertiary care institutions in Korea from 2018 to 2020.

Main Question Does the COVID-19 pandemic lead to more advanced stages of colorectal cancer at diagnosis and higher complication rates during surgery? Is there a significant difference in recurrence-free survival between CRC patients treated before and during the pandemic?

This study found that more patients presented with advanced-stage CRC during the COVID-19 pandemic, with significantly higher rates of tumor-related complications (perforations, abscesses, and preoperative obstructions), as well as an increase in open surgeries and combined resections.

No significant difference in recurrence-free survival was observed between the pre-COVID-19 and COVID-19 periods, although postoperative complication rates were higher, especially among rectal cancer patients and those receiving preoperative chemoradiotherapy.

Conditions

  • Colorectal Carcinoma
  • COVID 19

Sponsors & Collaborators

  • Kyungpook National University Chilgok Hospital

    collaborator OTHER
  • Gangnam Severance Hospital

    collaborator OTHER
  • Chonnam National University Hospital

    collaborator OTHER
  • Korea University Anam Hospital

    collaborator OTHER
  • Pusan National University Yangsan Hospital

    collaborator OTHER
  • Samsung Medical Center

    collaborator OTHER
  • Seoul Saint Mary's Hospital

    collaborator UNKNOWN
  • In Ja Park

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-01
Primary Completion
2020-12-31
Completion
2024-09-20

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06638957 on ClinicalTrials.gov