Impact of the COVID-19 Pandemic on Oncologic Outcomes in Colorectal Cancer
NCT06638957 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 14951
Last updated 2024-10-15
Summary
The goal of this observational study is to assess the impact of the COVID-19 pandemic on colorectal cancer (CRC) outcomes, particularly focusing on stage distribution and recurrence-free survival in patients undergoing surgery at eight tertiary care institutions in Korea from 2018 to 2020.
Main Question Does the COVID-19 pandemic lead to more advanced stages of colorectal cancer at diagnosis and higher complication rates during surgery? Is there a significant difference in recurrence-free survival between CRC patients treated before and during the pandemic?
This study found that more patients presented with advanced-stage CRC during the COVID-19 pandemic, with significantly higher rates of tumor-related complications (perforations, abscesses, and preoperative obstructions), as well as an increase in open surgeries and combined resections.
No significant difference in recurrence-free survival was observed between the pre-COVID-19 and COVID-19 periods, although postoperative complication rates were higher, especially among rectal cancer patients and those receiving preoperative chemoradiotherapy.
Conditions
- Colorectal Carcinoma
- COVID 19
Sponsors & Collaborators
-
Kyungpook National University Chilgok Hospital
collaborator OTHER -
Gangnam Severance Hospital
collaborator OTHER -
Chonnam National University Hospital
collaborator OTHER -
Korea University Anam Hospital
collaborator OTHER -
Pusan National University Yangsan Hospital
collaborator OTHER -
Samsung Medical Center
collaborator OTHER -
Seoul Saint Mary's Hospital
collaborator UNKNOWN -
In Ja Park
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-01-01
- Primary Completion
- 2020-12-31
- Completion
- 2024-09-20
Countries
- South Korea
Study Locations
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