MedTrace Logo

Exploring How Viral Infections Affect People With Chronic Lung Disease

NCT06625944 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 180

Last updated 2025-07-14

No results posted yet for this study

Summary

Many people with chronic lung disease have disease flare-ups. It was previously believed that these were mainly caused by bacteria but recent evidence suggests that viruses could be an important trigger. This study will recruit volunteers with chronic lung disease and take samples both when well (at baseline) and during flare-ups (exacerbations) to better understand the role of viruses in triggering exacerbations and also how the immune response is affected. The researchers will follow the volunteers\' progress for up to two years. Whenever they get unwell they will take some samples (nose swabs, finger prick testing, phlegm sample) and post them to the researchers. Then, they will come in for a visit for more samples (blood tests, further swabs) and a review.

Conditions

  • Bronchiectasis Adult
  • Bronchiectasis With Acute Exacerbation
  • COPD (Chronic Obstructive Pulmonary Disease)
  • Respiratory Infection Virus

Sponsors & Collaborators

  • Imperial College London

    lead OTHER

Principal Investigators

  • Anand Shah · Imperial College London

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-01
Primary Completion
2027-04-30
Completion
2027-04-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06625944 on ClinicalTrials.gov