Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors
NCT06587477 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2024-09-19
Summary
Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent cancer in Hong Kong. This can provide more information for pre-treatment counselling as well as improve post treatment survivorship care. The testicular function will be compared to aged-matched controls from men attending the Family Planning Association for premarital check-up.
Conditions
- Cancer, Treatment-Related
- Late Effect
- Semen Analysis
Interventions
- OTHER
-
Hormonal profile
Blood for FSH, LH, testosterone
- OTHER
-
Semen analysis
Semen analysis
- OTHER
-
Questionnaire
The European Male Ageing Study (EMAS) questionnaire
Sponsors & Collaborators
-
Queen Mary Hospital, Hong Kong
collaborator OTHER -
Prince of Wales Hospital, Shatin, Hong Kong
collaborator OTHER -
Hong Kong Children's Hospital
collaborator OTHER -
The University of Hong Kong
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-01-16
- Primary Completion
- 2027-12-31
- Completion
- 2028-06-30
Countries
- China
Study Locations
More Related Trials
-
Effect of Age on Sperm Recovery of Microdissection Testicular Sperm Extraction in Nonobstructive Azoospermia Patients
NCT05958576 ·Status: COMPLETED
-
Male Fertility Preservation Using Cryopreservation of Testicular Tissue Before Highly Gonadotoxic Cancer Treatment
NCT03180918 ·Status: RECRUITING ·Phase: NA
-
Survey of Patients Who Received Fertility Preservation Counseling and Underwent Testicular Tissue Cryopreservation Prior to Gonadotoxic Treatment During Childhood or Peripuberty
NCT07140549 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Short Term Genetic Effects of Chemotherapy on Male Germ Cells
NCT02975245 ·Status: COMPLETED
-
Testicular Tissue Cryopreservation for Fertility Preservation
NCT02972801 ·Status: RECRUITING ·Phase: NA
-
Effect of Letrozole on Seminal Parameters in Men With Non Obstructive Azoospermia and Severe Oligozoospermia.
NCT02900105 ·Status: COMPLETED ·Phase: PHASE3
-
Autologous Testicular Tissue Transplantation
NCT05414045 ·Status: RECRUITING ·Phase: NA
-
Machine Learning Based-Personalized Prediction of Sperm Retrieval Success Rate
NCT06358794 ·Status: COMPLETED
-
Sperm Retrieval Rates in Non-obstructive Azoospermic Men Subjected to Gonadotropin Therapy
NCT05110391 ·Status: COMPLETED
-
Testicular Tissue Cryopreservation for Fertility Preservation in Male Patients Facing Infertility-causing Diseases or Treatment Regimens
NCT02687880 ·Status: WITHDRAWN
-
Identifying Candidates for Limited Dissection at Microdissection TESE.
NCT07286279 ·Status: COMPLETED
-
Effect of Liver Cirrhosis on Semen Parameters and Reproductive Hormones
NCT03167749 ·Status: UNKNOWN
-
Fertility Preservation in Male AYA With Cancer
NCT04268004 ·Status: COMPLETED ·Phase: NA
-
Ejaculation Frequency and Semen Parameters
NCT06172504 ·Status: RECRUITING
-
Role of Antioxidants in the Reduction of Oxidative Stress in Infertile Patients
NCT05135143 ·Status: COMPLETED ·Phase: PHASE4
-
Semen Parameters and COVID-19 in Infertile Men
NCT04643522 ·Status: COMPLETED
-
Treatment of Severe Male Infertility - Predictive Factors (Imaging)
NCT02931721 ·Status: COMPLETED
-
Effects of a Fasting Mimicking Diet on Sperm Quality
NCT04908774 ·Status: COMPLETED ·Phase: NA
-
Male Fertility and Sperm Cryopreservation
NCT02431000 ·Status: WITHDRAWN
-
TESE and Non Obstructive Azoospermia
NCT03146260 ·Status: UNKNOWN ·Phase: NA
-
Anti-oxidative Influence From Pomegranate Tablets on Male Sperm Quality in Couples Undergo Infertility Treatments Due to Male Infertility.
NCT01918163 ·Status: UNKNOWN ·Phase: PHASE3
-
A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome
NCT03594201 ·Status: COMPLETED
-
Contraception in Normal and Subnormal Men
NCT00167141 ·Status: TERMINATED ·Phase: PHASE2
-
Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA
NCT06307639 ·Status: NOT_YET_RECRUITING
-
Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum
NCT00156650 ·Status: COMPLETED ·Phase: PHASE1/PHASE2