Lynch Syndrome Integrative Epidemiology and Genetics

Summary

The vision of the "Lynch syndrome INtegrative Epidemiology And GEnetics" (LINEAGE) Consortium is to collaboratively improve the lives and longevity of individuals and families with Lynch syndrome.

The mission of the LINEAGE Consortium is to collaboratively improve Lynch syndrome care through high-quality research. This consortium will provide intellectual and infrastructure support to facilitate development of research questions, collection of standardized data and biospecimens, support of grant applications, and generation of collaborative manuscripts.

Our aims are to:

I. Establish a prospective cohort of individuals with Lynch syndrome II. Collect standardized longitudinal clinical and biosample data to elucidate Lynch Syndrome epidemiology and gene-host interactions III. Promote intervention trials to improve cancer prevention and early detection in Lynch Syndrome

Conditions

• Lynch Syndrome

Sponsors & Collaborators

• University of Chicago

  collaborator OTHER

• University of Kansas

  collaborator OTHER

• University of Pennsylvania

  collaborator OTHER

• Johns Hopkins University

  collaborator OTHER

• City of Hope National Medical Center

  collaborator OTHER

• Loma Linda University

  collaborator OTHER

• MedStar Health

  collaborator OTHER

• University of Arizona

  collaborator OTHER

• University of Manitoba

  collaborator OTHER

• University of Michigan

  collaborator OTHER

• University of North Carolina

  collaborator OTHER

• University of Pittsburgh

  collaborator OTHER

• University of Rochester

  collaborator OTHER

• Dana-Farber Cancer Institute

  collaborator OTHER

• University of Wisconsin, Madison

  collaborator OTHER

• The Cleveland Clinic

  collaborator OTHER

• University of California, San Diego

  collaborator OTHER

• Kaiser Permanente

  collaborator OTHER

• Ohio State University

  collaborator OTHER

• Virginia Mason Hospital/Medical Center

  collaborator OTHER

• University of Alabama at Birmingham

  collaborator OTHER

• University of Miami

  collaborator OTHER

• University of Colorado, Denver

  lead OTHER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-10-01

Primary Completion

2054-12-31

Completion

2054-12-31

Countries

• United States

Study Locations