Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRC
NCT06551207 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2024-08-13
Summary
An assessment of 6-month progression-free survival in patients with mCRC with third-line and postline metastatic colorectal cancer in combination with cardonilizumab and fuquinitinib and SBRT compared with fuquinitinib monotherapy
Conditions
Interventions
- DRUG
-
Fruquintinib:5mg ,qd,po, d1-d14, q3w
- DRUG
-
Cadonilimab
Cadonilimab:10mg/kg, ivgtt, d1, q3w
- RADIATION
-
SBRT
SBRT:8-10Gy×5F, god, in 10 days
Sponsors & Collaborators
-
Liu Huang
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-08-20
- Primary Completion
- 2026-12-30
- Completion
- 2027-12-30
Countries
- China
Study Locations
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