Fruquintinib Combined With mFOLFOX6/FOLFIRI in First-line Treatment for Metastatic Colorectal Cancer
NCT05004441 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 43
Last updated 2022-10-26
Summary
The purpose of this study is to evaluate the efficacy and safety of Fruquintinib Combined With mFOLFOX6/FOLFIRI as the first-line treatment of Metastatic Colorectal Cancer
Conditions
Interventions
- DRUG
-
Fruquintinib Combined With mFOLFOX6/FOLFIRI
Fruquintinib (3mg) will be given p.o. daily
Sponsors & Collaborators
-
Hubei Cancer Hospital
collaborator OTHER -
Henan Cancer Hospital
collaborator OTHER_GOV -
Xiangya Hospital of Central South University
collaborator OTHER -
Huangshi Central Hospital
collaborator OTHER -
Zhou Fuxiang
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-07-22
- Primary Completion
- 2022-12-30
- Completion
- 2023-12-30
Countries
- China
Study Locations
More Related Trials
-
Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer
NCT04296019 ·Status: UNKNOWN ·Phase: PHASE2
-
Real World Study of Regorafenib Versus Fruquintinib in Colorectal Cancer
NCT04431791 ·Status: UNKNOWN
-
Fruquintinib in Refractory Metastatic Colorectal Cancer: A Real-world Study
NCT06202417 ·Status: COMPLETED
-
Fruquintinib Sequential BEV+FOLFIRI vs. BEV+FOLFIRI Sequential Fruquintinib in Metastatic Colorectal Cancer
NCT05447715 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Fuquinitinib Combined With Capecitabine First-line Maintenance in the Treatment of Metastatic Colorectal Cancer
NCT06115733 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
The Efficacy and Safety of Fruquintinib Plus Chemotherapy as Second-line Treatment in Metastatic Colorectal Cancer
NCT05555901 ·Status: UNKNOWN ·Phase: PHASE2
-
Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer
NCT06441565 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Clinical Study of Fruquintinib Combined With Raltitrexed in the Treatment of Metastatic Colorectal Cancer
NCT06118762 ·Status: RECRUITING ·Phase: PHASE4
-
Phase II Trial of FOLFOXIGIL Versus FOLFOXIRI as First-line Therapy in Patients With mCRC
NCT03222089 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Prospective, Open-label, Single-arm Phase II Clinical Study of Fruquintinib Combined With S-1 for the Treatment of Metastatic Colorectal Cancer.
NCT06746545 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Prospective Multi-centered Randomized Controlled Trial on Fruquintinib in Combination With HAIC in the Treatment of Liver Metastatic Colorectal Cancer After Failure of Second-line Systematic Therapy
NCT05511051 ·Status: UNKNOWN ·Phase: PHASE2
-
FOLFIRI Versus Irinotecan as Second-line Treatment in Metastatic Colorectal Cancer Patients
NCT02935764 ·Status: UNKNOWN ·Phase: PHASE3
-
FOLFOXIRI Compared to FOLFOX in First Line Treatment of Metastatic Colorectal Cancer
NCT02128425 ·Status: UNKNOWN ·Phase: PHASE2
-
Fruquintinib in the Cross-line Treatment of Refractory mCRC
NCT06099314 ·Status: RECRUITING
-
Fruquintinib Combined With TAS-102 in Refractory Metastatic Colorectal Cancer
NCT06221423 ·Status: RECRUITING
-
Fruquintinib Plus Camrelizumab and Capecitabine as Salvage Therapy After Progression on FOLFOXIRI-based First-line Treatment in Patients With Unresectable/Metastatic Colorectal Cancer
NCT06148402 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase Ib Study of Fruquintinib in 3rd Line mCRC
NCT01975077 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)
NCT07011576 ·Status: RECRUITING ·Phase: PHASE2
-
A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.
NCT05004350 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer
NCT07042685 ·Status: RECRUITING ·Phase: PHASE2
-
Fruquintinib Plus Camrelizumab and HAIC in the Treatment of Non-MSI-H Advanced Colorectal Cancer
NCT06423937 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Fruquintinib Combined With Chemotherapy as Third-line /Third-line+ Treatment in Advanced Colorectal Cancer
NCT05928312 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Phase III Trial Evaluating Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients (FRESCO)
NCT02314819 ·Status: COMPLETED ·Phase: PHASE3
-
Study of 5-fluorouracil (5-FU) in Patients With Metastatic Colorectal Cancer
NCT06501989 ·Status: WITHDRAWN ·Phase: PHASE2
-
Fruquintinib Plus S-1 and Raltitrexed (RSF) for MCRC
NCT06427005 ·Status: RECRUITING ·Phase: PHASE2