Fruquintinib Combined With TAS-102 in Refractory Metastatic Colorectal Cancer
NCT06221423 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2024-01-24
Summary
Fruquintinib, as a standard treatment for refractory metastatic colorectal cancer (mCRC), has attracted increasing research efforts to explore its innovative strategies in combination with immunotherapy and chemotherapy because of its multi-target mechanism which enhances the sensitivity of the immune system and chemotherapy, aiming to further improve the survival benefits for mCRC patients. Trifluridine/tipiracil (TAS-102) is also a standard treatment for mCRC. This study aims to investigate the safety and effectiveness of the combined use of these two drugs in mCRC.
Conditions
- Colorectal Cancer
- Metastatic Colorectal Cancer
- Refractory Colorectal Carcinoma
Interventions
- DRUG
-
Fruquintinib Combined With TAS-102
Fruquintinib Combined With TAS-102
Sponsors & Collaborators
-
Fudan University
lead OTHER
Principal Investigators
-
Jianmin Xu · Department of Colorectal Surgery, Zhongshan Hospital, Fudan University
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-01-01
- Primary Completion
- 2024-05-31
- Completion
- 2024-05-31
Countries
- China
Study Locations
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