Isometric Exercise for Hypertension
NCT06515054 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2025-12-16
Summary
Background: Isometric resistance exercises (IREs) have great potential to improve blood pressure (BP) control.
Methods: This is a pilot randomized controlled trial that will involve 50 patients with hypertension (HT) who do not meet the current physical activity guidelines defined by the World Health Organization. Participants will be randomly assigned in a 1:1 ratio using stratified and blocked randomization to either the IRE (wall squat) group or stretching exercise (active control) group. A well-structured, widely accepted, and validated 24-week wall squat program (2 minutes per exercise, 2 minutes of rest between sets, and 3 sessions per week) will be implemented, as it has been commonly used in previous research. All patients will be followed up for 24 weeks. Control group will receive exact same treatment except that IRE is replaced by frequency-matched and time-matched stretching exercise. The primary outcome measure will be rate of recruitment. Secondary outcomes will include BP parameters from 24-hour ambulatory BP monitoring
Conditions
Interventions
- BEHAVIORAL
-
wall squat
self-learnt wall squat exercise to be conducted for totally 24 weeks
- BEHAVIORAL
-
passive stretching
time-matched passive stretching exercise to be conducted for totally 24 weeks
Sponsors & Collaborators
-
Chinese University of Hong Kong
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-07-20
- Primary Completion
- 2025-09-30
- Completion
- 2025-11-30
Countries
- Hong Kong
Study Locations
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