Virtual perI-/Menopause Registry of AusTrALia

Summary

13 million (50.7%) Australians are born with ovaries, 14% (\~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as \>12 months without a period. Peri-menopause (peri), typically occurs 5 yrs before menopause as hormone levels decrease. As with oestrogen, peri symptoms can affect every bodily system; e.g. depression/anxiety, diminished mental function, irregular periods, hot flushes, sleep problems, vaginal atrophy \& urinary urgency. These symptoms are linked with lower quality of life \& significantly higher work impairment; a third experiencing symptoms so severe as to impede daily life \& increase risk of suicide. Lifetime increased risks of diabetes, heart disease, osteoporosis \& dementia are also associated with menopause, yet it remains disconcertingly poorly studied.

The investigators propose to create a world-first, cutting-edge, consumer-driven, Virtual peri-/menopause registry of AusTrALia (VITAL). The unique design will enable consumers to determine VITAL's questions, encourage secure revelation of private data e.g. vaginal \& mental health symptoms, \& to direct priorities for research, education, \& health service improvements. VITAL will thus deliver optimal assessments of incidence, prevalence \& impact.

The participating consumers, researchers, clinical specialists, policy makers, \& modern virtual data infrastructure enable this unique \& innovative registry design, future translation to improved community health, \& promote awareness \& collaborative synergies. Leveraging the investigators' critical range of expertise \& ongoing feedback opportunities for both participants \& stakeholder partnerships, the investigators will create a ground-breaking platform that:

* empowers the consumer voice and priorities,
* enables peri-/menopause research to extend beyond existing niche focuses,
* evidences the true impact of peri-/menopause across the nation,
* evolves healthcare services and outcomes, \&
* educates community, clinicians, \& policy-makers. After Australian registry establishment, the investigators will expand VITAL to mirror it in other nations while still protecting individual's data the right way, but so all can learn \& apply the best aspects of care from across the world.

Conditions

• Menopause
• Perimenopausal Disorder
• Postmenopausal Symptoms
• Health Knowledge, Attitudes, Practice
• Healthy Aging
• Health Care Utilization
• Health Care Seeking Behavior
• Mental Health Impairment
• Mental Deterioration
• Mental Health Issue
• Osteoporosis, Postmenopausal
• Diabetes Mellitus Risk
• Diabetes Mellitus, Type 2
• Dementia
• Cardiovascular Diseases
• Menopause Related Conditions
• Hot Flashes
• Hot Flushes Aggravated
• Economic Burden
• Social Stigma

Interventions

OTHER

N/A Observational Registry

Registry participants may select to be contacted for future research and/or embedded clinical trials. Such interventions will require associated ethics review \& approval.

Sponsors & Collaborators

• Bespoke Clinical Research

  lead INDUSTRY

Principal Investigators

• Erin B Morton, PhD,Medicine · Bespoke Clinical Research

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-08-03

Primary Completion

2073-08-31

Completion

2073-08-31

Countries

• Australia

Study Locations