Dysfunction of Olfaction After COVID-19 Infection: Morphological and Histomolecular Investigation

NCT06482138 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 240

Last updated 2026-05-06

No results posted yet for this study

Summary

Investigation of the mechanisms of persistent SARS-CoV-2 associated olfactory dysfunction (OD) in patients with well-documented olfactory function. The investigators plan to collect olfactory cleft biopsies and cytobrushes in COVID-19 patients and controls.

Conditions

  • Covid19
  • Olfactory Dysfunction

Interventions

PROCEDURE

Biopsy and Cytobrush

Collection of olfactory cleft biopsies and cytobrushes

Sponsors & Collaborators

  • University Hospital, Geneva

    collaborator OTHER
  • Max Planck Research Unit for Neurogenetics

    collaborator UNKNOWN
  • University Hospital Carl Gustav Carus

    collaborator OTHER
  • University of Zurich

    collaborator OTHER
  • Universitaire Ziekenhuizen KU Leuven

    lead OTHER

Principal Investigators

  • Laura van Gerven · UZ/KU Leuven

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-24
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Belgium
  • Germany
  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06482138 on ClinicalTrials.gov