Clinical Treatment Research of COVID-19-related Olfactory Dysfunction
NCT05421195 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 124
Last updated 2022-06-22
Summary
Studies have demonstrated that patients with COVID-19- related olfactory dysfunction could improve the olfactory function after olfactory training. But the efficacy of oral corticosteroids is controversial. Some evidences shown that corticosteroid treatment would benefit post-COVID-19 olfactory dysfunction and the purpose of this study is to evaluate its efficacy.
Conditions
- Olfactory Dysfunction
Interventions
- DRUG
-
corticosteroids therapy
Oral corticosteroids
- OTHER
-
Olfactory training
repeat and deliberate sniffing of a set of odorants
Sponsors & Collaborators
-
Eye & ENT Hospital of Fudan University
lead OTHER
Principal Investigators
-
Hongmeng Yu, Dr · Eye & ENT Hospital, Fudan University
-
Xicai Sun, Dr · Eye&ENT Hospital,Fudan University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-17
- Primary Completion
- 2023-02-01
- Completion
- 2023-03-01
Countries
- China
Study Locations
More Related Trials
-
Anosmia and Covid-19
NCT05246059 ·Status: COMPLETED ·Phase: NA
-
Stellate Ganglion Block for COVID-19-Induced Olfactory Dysfunction
NCT05445921 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Smell in Covid-19 and Efficacy of Nasal Theophylline
NCT04789499 ·Status: COMPLETED ·Phase: PHASE2
-
Corticosteroid Nasal Spray in COVID-19 Anosmia
NCT04484493 ·Status: COMPLETED ·Phase: PHASE3
-
Anosmia Rehabilitation in Patients Post Coronavirus Disease (COVID 19)
NCT04374474 ·Status: WITHDRAWN ·Phase: PHASE4
-
Study of the Pathogenesis of Olfactory Disorders in COVID-19
NCT04366934 ·Status: COMPLETED
-
Treatment of Pediatric Patients That Lost Sense of Smell Due to COVID-19
NCT04964414 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
NCT05855369 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Effect of Nasal Steroid in the Treatment of Anosmia Due to COVID-19 Disease
NCT04569825 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Olfactory Training As a Treatment for Olfactory Dysfunction Post COVID-19
NCT05384561 ·Status: RECRUITING ·Phase: NA
-
The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRS
NCT06837051 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Acupuncture for Olfactory Dysfunction in Infected COVID-19 Patients
NCT04959747 ·Status: UNKNOWN ·Phase: NA
-
COVID-19 Anosmia Study
NCT04495816 ·Status: COMPLETED ·Phase: PHASE2
-
Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction
NCT06204432 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Coronavirus Smell Therapy for Anosmia Recovery
NCT04422275 ·Status: WITHDRAWN ·Phase: PHASE2
-
Ivermectin Nasal Drops in Post COVID-19 Parosmia
NCT05269030 ·Status: UNKNOWN ·Phase: PHASE2
-
Simvastatin Nasal Rinses for the Treatment of COVID-19 Mediated Dysomsia
NCT05542095 ·Status: WITHDRAWN ·Phase: PHASE1
-
Trial of Directed High-dose Nasal Steroids on Residual Smell Loss in Sinus Patients After Sinus Surgery
NCT01814618 ·Status: WITHDRAWN ·Phase: PHASE2
-
Dysfunction of Olfaction After COVID-19 Infection: Morphological and Histomolecular Investigation
NCT06482138 ·Status: RECRUITING ·Phase: NA
-
Study of the Evolution of Olfactory Disorders in Patients With Persistent Loss of Smell Following COVID-19
NCT05133596 ·Status: COMPLETED ·Phase: NA
-
Stellate Ganglion Block with Lidocaine for the Treatment of COVID-19-Induced Parosmia
NCT06055270 ·Status: RECRUITING ·Phase: PHASE3
-
Stellate Ganglion Block for COVID-induced Parosmia
NCT06253806 ·Status: COMPLETED ·Phase: PHASE2
-
Steroid Nasal Irrigation for Flavor Evaluation and Detection Study
NCT02985515 ·Status: COMPLETED ·Phase: NA
-
CST1-Guided Oral Glucocorticoids Management for CRSwNP
NCT05598411 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Smell Changes & Efficacy of Nasal Theophylline
NCT03990766 ·Status: COMPLETED ·Phase: PHASE2