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Determinants of Olfactory Dysfunction in Chronic Rhinosinusitis

NCT02720653 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 418

Last updated 2022-04-20

No results posted yet for this study

Summary

Olfactory dysfunction is a cardinal symptom of chronic rhinosinusitis, a disease which affects 12.5% of the adult population across all racial and ethnic groups. Previous research has documented olfactory deficit in 68% of patients with chronic rhinosinusitis and 20% with complete anosmia, suggesting that olfactory dysfunction affects over 25 million individuals in the United States with chronic rhinosinusitis. This proposed investigation will be used to predict olfactory outcomes following treatments for chronic rhinosinusitis and gain insights into mechanisms of olfactory dysfunction in this population.

Conditions

  • Chronic Rhinosinusitis
  • Olfactory Dysfunction

Interventions

PROCEDURE

Endoscopic sinus surgery

Sponsors & Collaborators

  • Medical University of South Carolina

    collaborator OTHER

  • Oregon Health and Science University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-07-01
Primary Completion
2022-06-30
Completion
2022-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02720653 on ClinicalTrials.gov