Predicting Early Tumor Recurrence in Patients With Esophageal Squamous Cell Carcinoma
NCT06476067 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2025-07-11
Summary
The prognosis of patients with esophageal squamous cell carcinoma (ESCC) who develop post-operative early tumor recurrence is often relatively poor. Therefore, biomarker that can detect micro metastases before the start of treatment is required. Epigenomic alterations such as DNA methylation have attracted attention as promising biomarkers. The investigators aim to predict early recurrence based on whole genome DNA methylation analysis of esophageal cancer.
Conditions
- Esophageal Cancer
- Recurrence
- DNA Methylation
Interventions
- PROCEDURE
-
Surgery
Esophagectomy
Sponsors & Collaborators
-
City of Hope Medical Center
lead OTHER
Principal Investigators
-
Koichi Takiguchi, PhD · City of Hope Medical Center
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-01-01
- Primary Completion
- 2026-06-18
- Completion
- 2026-06-18
Countries
- Japan
Study Locations
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