China Early Esophageal Cancer Cohort

Summary

With the development of endoscopy, more and more patients with superficial esophageal squamous cell carcinoma (ESCC) receive endoscopic resection rather than traditional surgery. However, there is still no complete consensus on the risk factors for lymph node metastasis (LNM) and recurrence of ESCC after endoscopic resection. The existing curative resection criteria are strict to a certain extent, and a considerable number of patients are overtreated according to the current standard of additional treatment. Thus, we aim to conduct a multi-center retrospective and prospective study to construct a large cohort of ESCC based on the previously established multi-center collaborative research network and clinical big data, analyze the risk factors of LNM and recurrence in patients with early esophageal squamous cell carcinoma after ESD, establish an accurate and simple risk prediction model, and evaluate the discrimination efficiency of this model.

Conditions

• Early Esophageal Cancer

Interventions

OTHER

observational study

observational study, no intervention

Sponsors & Collaborators

• Lianshui People's Hospital

  collaborator UNKNOWN

• The second affiliated hospital of Xuzhou medical university

  collaborator UNKNOWN

• The second people's hospital of Nanyang

  collaborator UNKNOWN

• Nanchong Central Hospital

  collaborator OTHER_GOV

• Tongliao City Hospital

  collaborator UNKNOWN

• Yancheng First People's Hospital

  collaborator OTHER

• The Second Hospital of Hebei Medical University

  collaborator OTHER

• The Second Affiliated Hospital of Baotou Medical College

  collaborator OTHER

• Affiliated Hospital of Southwest Medical University

  collaborator OTHER

• Sichuan Cancer Hospital and Research Institute

  collaborator OTHER

• The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

  collaborator OTHER

• Zhongda Hospital

  collaborator OTHER

• The First Affiliated Hospital with Nanjing Medical University

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• The First Affiliated Hospital of Soochow University

  collaborator OTHER

• Jiangsu Province Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• Shanxi Provincial People's Hospital

  collaborator OTHER_GOV

• Henan Provincial People's Hospital

  collaborator OTHER

• Anyang Cancer Hospital

  collaborator UNKNOWN

• Changhai Hospital

  lead OTHER

Eligibility

Min Age

15 Years

Max Age

85 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-10-01

Primary Completion

2025-10-01

Completion

2025-10-01

Countries

• China

Study Locations