Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma
NCT06490003 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2025-07-11
Summary
Esophageal cancer remains a disease with a poor prognosis. Chemotherapy is an important part of its treatment, but there are cases in which chemotherapy is ineffective. The investigators aim to develop a model to predict the response to chemotherapy by DNA methylation of preoperative biopsy specimens to identify the chemotherapy ineffective group.
Conditions
- Esophageal Squamous Cell Carcinoma
- Chemotherapy Effect
- DNA Methylation
Interventions
- DRUG
-
Fluoro Uracil
Esophageal cancer chemotherapy(First line treatment)
Sponsors & Collaborators
-
City of Hope Medical Center
lead OTHER
Principal Investigators
-
Koichi Takiguchi, PhD · City of Hope Medical Center
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-06-01
- Primary Completion
- 2026-06-18
- Completion
- 2026-06-18
Countries
- Japan
Study Locations
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