The Antagonistic Effect of Composite Polyphenols on Health Damage Caused by Environmental Pollutants
NCT06437119 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 98
Last updated 2026-04-06
Summary
The study attempts to conduct randomized controlled trials to understand whether daily exposure to environmental pollutants can cause harm to human health, explore whether the intake of composite polyphenols can alleviate potential health hazards caused by environmental pollutants, and provide scientific basis for the prevention and treatment of health hazards caused by environmental pollutant exposure.
Conditions
- Intestinal Functional Disorder
- Inflammation
Interventions
- DIETARY_SUPPLEMENT
-
Compound plant nutrients
The main active components of the composite polyphenols intervention agent include a mixture of 43 types of polyphenols. The composite polyphenols intervention agent is powders encapsulated in sachets, each containing 155 mg composite polyphenols.
- DIETARY_SUPPLEMENT
-
placebo
The placebo mainly consists of resistant dextrin and erythritol. Apart from the contents, the appearance, color, and consumption method of the placebo are the same as those of the intervention agent. Participants were not informed of their group allocation in any way.
Sponsors & Collaborators
-
Amway (China) Daily-Use Commodity Co.,Ltd
collaborator UNKNOWN -
Fudan University
lead OTHER
Principal Investigators
-
Ruihua Dong · School of Public Health,Fudan University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-04-23
- Primary Completion
- 2024-10-01
- Completion
- 2024-12-31
Countries
- China
Study Locations
More Related Trials
-
Plant-Based Foods and (Poly)Phenol Supplementation in Gut Microbiota Modulation, Body Weight, and Cardiometabolic Risk
NCT06911346 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Bioavailability of Aronia Berry Polyphenols
NCT05488886 ·Status: COMPLETED ·Phase: NA
-
China Plant Sterol Trial
NCT00145717 ·Status: COMPLETED ·Phase: PHASE3
-
A Specialized Nutraceutical for Pre-burnout
NCT04532892 ·Status: COMPLETED ·Phase: NA
-
Dietary Polyphenols and Lipid Oxidation
NCT01302639 ·Status: COMPLETED ·Phase: NA
-
Effects of Polyphenols on Iron Absorption in Iron Overload Disorders.
NCT03453918 ·Status: COMPLETED ·Phase: NA
-
Effects of Short-term Curcumin and Multi-polyphenol Supplementation on the Anti-inflammatory Properties of HDL
NCT02998918 ·Status: COMPLETED ·Phase: NA
-
Natural Modulators of Immune Function and Mood
NCT05508529 ·Status: COMPLETED ·Phase: NA
-
Gut Microbial Metabolism of Polyphenols and Cardiovascular Health (StratiPol) (Stratification Study)
NCT03573414 ·Status: UNKNOWN ·Phase: NA
-
Dietary Supplementation on Gastrointestinal Barrier Function
NCT06262880 ·Status: RECRUITING ·Phase: NA
-
A Clinical Study of De-Stress & Chill Gummies in Reducing Stress
NCT06571071 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Intervention Effect of TP and AOB-w on Acrylamide Exposure in Chinese Adolescents
NCT03118167 ·Status: COMPLETED ·Phase: NA
-
A Double Blind Study on the Gastrointestinal Effects of Arabinoxylan (Leaf Fiber Extract).
NCT04100460 ·Status: UNKNOWN ·Phase: NA
-
Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)
NCT00721643 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Influences of Multivitamin Supplementation on Health Parameters
NCT03071796 ·Status: COMPLETED ·Phase: NA
-
Bioavailability and Bioactivity of Mango Polyphenols.
NCT06182540 ·Status: COMPLETED ·Phase: NA
-
Improving Everyday Functioning in Adults Aged 70 and Over Using a Multivitamin Supplement
NCT04112732 ·Status: COMPLETED ·Phase: NA
-
Effect of a Food Supplementation With a Combined Food Supplement on Lipid Pattern, Indexes of Non-alcoholic Fatty Liver Disease and Systemic Inflammation
NCT06247137 ·Status: COMPLETED ·Phase: NA
-
A Pilot Study to Characterize the Bioavailability and Plasma Profile of Potato Polyphenols in Humans
NCT02167607 ·Status: COMPLETED ·Phase: NA
-
Adding Polyphenol-rich Pulses to Daily Diet Improves Skin Health by Reshaping the Skin Microbiome
NCT06538415 ·Status: RECRUITING ·Phase: NA
-
Effects of Botanical Microglia Modulators in Gulf War Illness
NCT02909686 ·Status: COMPLETED ·Phase: NA
-
Broccoli Supplement Dose Response
NCT03399656 ·Status: COMPLETED ·Phase: NA
-
Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C Levels
NCT06403748 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Matrix on Fruit Constituent Bioavailability
NCT01908634 ·Status: COMPLETED ·Phase: NA
-
Quantifiably Determine if the Botanical Formulation, LLP-01, Has a Significant Clinical Effect on Proteomic Inflammatory and Cardiovascular Biomarkers in Healthy, Older Individuals.
NCT06065241 ·Status: COMPLETED ·Phase: NA