The Effect of Omega 3 Supplementation on Postoperative Delirium in Elderly Patients Undergoing Major Cardiac Surgery
NCT06434948 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 1
Last updated 2026-05-11
Summary
The purpose of this study is to determine whether giving omega-3 fatty acids prior to and after cardiac bypass surgeries decreases the incidence of postoperative delirium in patients aged 65 and over.
Conditions
- Postoperative Delirium
Interventions
- DRUG
-
Omega-3 Ethyl Esters 4 g
4 grams = 4 capsules, once daily
- DRUG
-
Omega-3 Ethyl Esters 2 g
2 grams = 2 capsules, once daily
Sponsors & Collaborators
-
University of Missouri-Columbia
lead OTHER
Principal Investigators
-
Quinn Johnson, MD · University of Missouri-Columbia
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-03-03
- Primary Completion
- 2026-04-29
- Completion
- 2026-04-29
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
The Emerging Role of Resolvins in the Prevention of Chronic Pain After Thoracic Surgery
NCT03095157 ·Status: UNKNOWN ·Phase: NA
-
Preoperative Intravenous Omega 3 Fatty Acids Administration in Valvular Surgery Patients
NCT00890838 ·Status: COMPLETED ·Phase: PHASE4
-
Omega-3 Fatty Acids and Postoperative Complications After Colorectal Surgery
NCT00488904 ·Status: COMPLETED ·Phase: PHASE4
-
Omega-3D: Omega-3 for Diet-Driven Health Disparities
NCT07078344 ·Status: RECRUITING ·Phase: PHASE2
-
Pharmacokinetics of Omega-3 Monoglycerides
NCT04382027 ·Status: COMPLETED ·Phase: NA
-
Effect of Omega-3 Fatty Acids on the Perioperative Immune Response and Erythrocyte Function
NCT02231203 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Omega-3 Fatty Acids on Bone and Frailty
NCT00634686 ·Status: UNKNOWN ·Phase: PHASE4
-
Evaluating the Effects of Omega-3 Fatty Acids on Heart Disease and Behavior
NCT00663871 ·Status: COMPLETED ·Phase: NA
-
Study to Assess the Effect of Intravenous Supplementation of Omega-3 Fatty Acids on Outcome of Recipients in Living Donor Liver Transplantation
NCT04030065 ·Status: UNKNOWN ·Phase: PHASE2
-
Fish Oil In Heart Transplantation
NCT01072994 ·Status: UNKNOWN ·Phase: NA
-
Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients
NCT06279793 ·Status: RECRUITING ·Phase: PHASE2
-
Cardioprotective Effects of Omega-3 Fatty Acids Supplementation in Healthy Older Subjects Exposed to Air Pollution Particles
NCT01442480 ·Status: COMPLETED ·Phase: NA
-
Effect of Supplemental Intake of Omega-3 Polyunsaturated Fatty Acids on the Rate and Complexity of Spontaneously Occurring Ventricular and Supraventricular Arrhythmias in Patients With Implantable Cardioverter Defibrillator (ICD) - A Randomized Clinical Trial
NCT00290056 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Omega -3 Fatty Acids Supplements and Plant Sterol Enriched Food in Dyslipidemic Adults
NCT00422266 ·Status: COMPLETED ·Phase: PHASE3
-
Omega 3 Fatty Acids and Atrial Fibrillation
NCT00508248 ·Status: WITHDRAWN ·Phase: NA
-
Effect of Omega 3 Fatty Acids on Vascular Function
NCT01888211 ·Status: COMPLETED ·Phase: NA
-
Fish Oil and Cardiovascular Suboptimal Health
NCT02103517 ·Status: COMPLETED ·Phase: PHASE3
-
Do Fish Oils Prevent Restenosis Post-Coronary Angioplasty?
NCT00000473 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of High-dose n-3 Fatty Acids on Clinical Outcome and Serum Lipids - Omacor Following Acute Myocardial Infarction
NCT01422317 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of a Fish Oil Containing Lipid Emulsion
NCT01176695 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Re-esterified Triglyceride (rTG) Form Omega-3 Supplements on Dry Eye Following Cataract Surgery
NCT04411615 ·Status: UNKNOWN ·Phase: NA
-
Effect of 12 wk of Omega-3 FA Supplementation on Metabolic and Physical Health Parameters in Older Adults
NCT01734538 ·Status: UNKNOWN ·Phase: NA
-
Omega 3 Polyunsaturated Fatty Acid Supplements (PUFAs) and Microvolt T Wave Alternans (TWA) in Patients With Ventricular Arrhythmia
NCT00507390 ·Status: WITHDRAWN ·Phase: PHASE4
-
Vascular and Lipid Effects of Omega-3 Fatty Acids in People With Moderately Elevated Triglycerides
NCT00504309 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Omega-3 Fatty Acid Therapy in Preventing Gastrointestinal Bleeding in Patients With CF-LVAD
NCT03784963 ·Status: TERMINATED ·Phase: PHASE1/PHASE2