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Preoperative Carbohydrate Load and Intraoperative w3-PUFA in CAGB Surgery

NCT03017001 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2017-01-11

No results posted yet for this study

Summary

Omega-3 polyunsaturated fatty acids (w-3-PUFA) may have a potential role in enhance the postoperative balance of host immunity and reduce the incidence of postoperative atrial fibrillation (POAF). CHO drinks 2h before the induction of the anesthesia may reduce the necessity of vasoactive drugs preoperatively. the aim of this study was to investigate the effect of these two nutrients in patients undergoing CABG with cardiopulmonary bypass (CPB) on morbidity at ICU, mainly POFA. This is a double-blind controlled randomized trial.

Conditions

  • Atrial Fibrillation Rapid
  • Postoperative Complications

Interventions

DIETARY_SUPPLEMENT

CHO (carbohydrate)

Patients in this group received a preoperative fast for solids for 6h and a drink containing water plus 12.5% maltodextrine (carbohydrate) 2h before anesthesia

DRUG

intravenous w-3 PUFA

Patients in this groups received during the operation (intraoperative) a dose of intravenous w3-PUFA

OTHER

CHO (carbohydrate) plus intravenous w3-PUFA

Patients in this group received a preoperative fast for solids for 6h and a drink containing water plus 12.5% maltodextrine (carbohydrate) 2h before anesthesia, plus an intravenous dose of w3-PUFA intraoperatively

Sponsors & Collaborators

  • Federal University of Mato Grosso

    lead OTHER

Principal Investigators

  • Jose Aguilar-Nascimento, MD; PhD · Federal University of Mato Grosso

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2016-06-30
Completion
2016-10-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03017001 on ClinicalTrials.gov