Pharmacokinetics of Antibiotics During Extracorporeal Membrane Oxygenation (ECMO) Support
NCT03922451 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 4
Last updated 2022-03-21
Summary
This study will measure plasma concentrations of piperacillin-tazobactam and cefazolin in pediatric patients supported with extracorporeal membrane oxygenation (ECMO) aiming to better understand the pharmacokinetics of these medications in this in vivo setting.
Conditions
- Drug Effect
Interventions
- DRUG
-
piperacillin-tazobactam
Administered for infection treatment or prophylaxis per hospital protocol
- DRUG
-
Cefazolin
Administered for infection treatment or prophylaxis per hospital protocol
Sponsors & Collaborators
- lead OTHER
Eligibility
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-08-27
- Primary Completion
- 2020-04-01
- Completion
- 2022-02-28
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Safety and Pharmacokinetics of Piperacillin-tazobactam Extended Infusion in Infants and Children (PIP-TAZO)
NCT02466438 ·Status: UNKNOWN ·Phase: PHASE1
-
Precision Dosing of Beta-lactam Antibiotics in Critically Ill Children
NCT06929702 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Pharmacokinetics and Safety of Piperacillin-tazobactam in Neonates
NCT00873327 ·Status: COMPLETED ·Phase: PHASE1
-
BL Infusion Trial:Beta-lactam Continuous Versus Intermittent Infusion and Associated Bacterial Resistance and Therapy Outcomes in Critically Ill Patients With Severe Pneumonia
NCT05102162 ·Status: TERMINATED ·Phase: PHASE4
-
Ambulatory Administration of Meropenem With Elastomeric Pumps and an Isothermal Pouch
NCT04809259 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Early Termination of Empirical Antibiotics in Febrile Neutropenia in Children With Cancer
NCT04637464 ·Status: COMPLETED ·Phase: NA
-
Pharmacokinetics of Colistin in Critically Ill Patients With Extracorporeal Membrane Oxygenation
NCT05542446 ·Status: TERMINATED ·Phase: PHASE4
-
A Study the Population Pharmacokinetics of Children of Infectious Disease in Central Nervous System
NCT03960905 ·Status: UNKNOWN
-
Clinical Outcomes With Ceftolozane-tazobactam for MDR Pseudomonas Infections
NCT03510351 ·Status: COMPLETED
-
Plasma Pharmacokinetics (PK) & Lung Penetration of Ceftolozane/Tazobactam in Participants With Pneumonia (MK-7625A-007)
NCT02387372 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics of Piperacillin and Tazobactam in Critically Ill Patients
NCT03738683 ·Status: COMPLETED
-
Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection
NCT04238390 ·Status: WITHDRAWN ·Phase: PHASE3
-
Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants.
NCT04126031 ·Status: TERMINATED ·Phase: PHASE2
-
Antibiotic Dosing in Pediatric Intensive Care
NCT02456974 ·Status: RECRUITING
-
Early Versus Late Stopping of Antibiotics in Children With Cancer and High-risk Febrile Neutropenia
NCT04948463 ·Status: COMPLETED ·Phase: PHASE4
-
Population Pharmacokinetic-pharmacodynamic (PK-PD) Study of 9 Broad-Spectrum Anti-infective Agents in the Cerebro Spinal Fluid (CSF) of Brain Injured Patients With an External Ventricular Drainage (EVD).
NCT03481569 ·Status: COMPLETED ·Phase: PHASE1
-
Antibiotics Distribution Study in Peripheral Compartments: Contribution of Microdialysis
NCT07327502 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Management of Ventilation Acquired Pneumonia Caused by Pseudomonas and Acinetobacter Organisms in a Pediatric Center
NCT06739382 ·Status: COMPLETED ·Phase: PHASE3
-
Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation
NCT04673175 ·Status: TERMINATED ·Phase: PHASE4
-
Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients with Ventilator Associated-pneumonia
NCT03581370 ·Status: RECRUITING ·Phase: PHASE3
-
Pharmacokinetics and Safety of Ticarcillin-clavulanate in Infants
NCT01229046 ·Status: WITHDRAWN ·Phase: PHASE1
-
Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections
NCT00621192 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Steady State Serum and Epithelial Lining Fluid (ELF) Antibiotics Concentrations Under Continous Infusion
NCT00435305 ·Status: TERMINATED
-
AbioKin - Antibiotic Kinetics
NCT02609646 ·Status: COMPLETED
-
Comparative Effectiveness of Intravenous v. Oral Antibiotic Therapy for Serious Bacterial Infections
NCT02311452 ·Status: COMPLETED