Evaluation of Impedance Cardiography for Assessing Hemodynamic Shifts in Patients With LA-NSCLC During Treatment.
NCT06277388 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 231
Last updated 2026-03-11
Summary
This study aimed to investigate the role of impedance cardiography (ICG) in evaluating hemodynamic changes during the 6-minute walk test (6MWT) in patients with locally advanced non-small cell lung cancer (LA-NSCLC) who underwent combined concurrent chemoradiotherapy (CCRT) and immunotherapy. Additionally, It sought to analyze the predictive significance of cardiac parameters to both treatment toxicity and survival prognosis.
Conditions
- Non-small Cell Lung Cancer
- Cardiac Toxicity
Interventions
- DEVICE
-
Impedance cardiography
The study conducted a 6-minute walk test (6MWT) in a hospital hallway following ATS guidelines. Patients rested for 10 minutes before the test. Impedance measurements were taken before (2 minutes), during (6 minutes), and after (3 minutes) the walk, recording cardio-dynamic parameters with impedance cardiography (ICG).
Sponsors & Collaborators
-
Sun Yat-sen University
lead OTHER
Principal Investigators
-
Hui Liu, MD · Sun Yat-sen University
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-06-05
- Primary Completion
- 2025-09-30
- Completion
- 2026-06-30
- FDA Device
- Yes
Countries
- China
Study Locations
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