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Stratification of Risks of Conversion of Radiologically Isolated Syndromes (RIS) by Identifying Biomarkers in Serum and Cerebrospinal Fluid.

NCT06395662 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 320

Last updated 2024-11-01

No results posted yet for this study

Summary

Radiologically isolated syndrome (RIS) often precedes Multiple Sclerosis (MS) but some patients have no symptoms. This study aims to use biological samples and magnetic resonance imaging (MRI) data from four large cohorts of patients with MS in the United States, Europe and France, to stratify the chances of RIS developing into MS. Identifying early biomarkers to predict greater disease severity would have a significant impact, not only on RIS but also on the entire clinical spectrum of multiple sclerosis.

Conditions

Interventions

OTHER

Observational

Search for biomarkers

Sponsors & Collaborators

  • International Center of Research in Infectiology, Lyon University

    collaborator UNKNOWN

  • Universite Cote d'Azur

    collaborator OTHER

  • The University of Texas at Dallas

    collaborator OTHER

  • Centre Hospitalier Universitaire de Nīmes

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-04-15
Primary Completion
2024-12-31
Completion
2025-07-31

Countries

  • United States
  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06395662 on ClinicalTrials.gov