PeRforation EVents During ENdovascular Therapy for Acute Ischemic Stroke
NCT06394180 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2026-03-09
Summary
A large, worldwide study called PREVENT is looking at a complication that can happen during a stroke treatment called thrombectomy. This complication is a perforation of a blood vessel. The investigators aim to:
1. Find what factors make this perforation more likely.
2. Understand why the perforation happens by looking closely at images taken during the procedure.
3. Create a simple way to classify these perforations to help doctors decide how to treat them right away.
4. Improve the emergent treatment of vessel perforation to stop the bleeding rapidly.
5. Provide data to guide decision whether thrombectomy should be continued or aborted after the event of vessel perforation.
6. Develop a safer way to perform thrombectomy.
Investigators will compare the results collected for patients where perforation happened with those where perforation did not happen.
Conditions
- Periprocedural Vessel Perforation
- Acute Ischemic Stroke
Sponsors & Collaborators
-
University Hospital, Basel, Switzerland
lead OTHER
Principal Investigators
-
Victor Schulze-Zachau, MD · University Hospital, Basel, Switzerland
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-12-02
- Primary Completion
- 2026-12-31
- Completion
- 2027-09-30
Countries
- Switzerland
Study Locations
More Related Trials
-
A Prospective Evaluation of Clinical Outcomes in Acute Ischemic Stroke After Endovascular Treatment w/Doppler
NCT07013396 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Which Factors Influence the Duration and the Success of Mechanical Thrombectomy During the Acute Phase of Cerebral Infarction?
NCT03451903 ·Status: COMPLETED
-
Thrombus Composition in Ischemic Stroke: Analysis of the Correlation With Plasma Biomarkers, Efficacy of Treatment, Etiology and Prognosis
NCT03268668 ·Status: RECRUITING
-
Randomization of Endovascular Treatment in Acute Ischemic Stroke in the Extended Time Window
NCT04256096 ·Status: UNKNOWN ·Phase: PHASE3
-
Registry for Evaluating Outcome of Acute Ischemic Stroke Patients Treated With Mechanical Thrombectomy.
NCT03496064 ·Status: COMPLETED
-
Mechanical Thrombectomy Of Acute Occlusion In Ischemic Stroke
NCT03144960 ·Status: UNKNOWN ·Phase: NA
-
Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe
NCT06825897 ·Status: RECRUITING ·Phase: NA
-
Endovascular Therapy for Large Core Patients With Uncertain Response to Thrombectomy
NCT06961487 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Endovascular Treatment for Mild Ischemic Stroke Due to Acute Large Vessel Occlusion in the Anterior Circulation
NCT06464731 ·Status: RECRUITING ·Phase: NA
-
Prediction of Patient-specific Outcomes After Interventional neuroRadiology Procedures
NCT04504695 ·Status: UNKNOWN
-
Minor Stroke Therapy Evaluation
NCT03796468 ·Status: RECRUITING ·Phase: NA
-
Predictive Factors of Outcome of Mechanical Thrombectomy After Acute Ischemic Stroke
NCT03608644 ·Status: UNKNOWN
-
Thrombolysis and RIPC in Acute Ischemic Stroke
NCT03218293 ·Status: COMPLETED ·Phase: NA
-
Reasons for Prehospital Delay in Patients With Acute Ischemic Stroke
NCT02798770 ·Status: COMPLETED
-
Direct Intra-arterial Thrombectomy in Order to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals
NCT03469206 ·Status: COMPLETED ·Phase: NA
-
The Prediction of Hemorrhage Transformation by Cerebral Autoregulation in AIS Patient After Endovascular Thrombectomy
NCT06361017 ·Status: ENROLLING_BY_INVITATION
-
Prevention and Treatment of Reperfusion Injury After Mechanical Thrombectomy in Acute Ischemic Stroke
NCT05282290 ·Status: UNKNOWN ·Phase: NA
-
Early Neurological Clinical Recovery, 3 Months After Endovascular Treatment of an Acute Ischemic Stroke
NCT02879123 ·Status: RECRUITING
-
PREvention of VENous Thromboembolism In Hemorrhagic Stroke Patients
NCT01573169 ·Status: TERMINATED ·Phase: PHASE3
-
Protocol-guided Rapid Evaluation of Veterans Experiencing New Transient Neurological Symptoms
NCT02769338 ·Status: COMPLETED ·Phase: NA
-
Mechanical Thrombectomy of Acute Ischemic Stroke Anterior Circulation Distal Vessel Occlusion
NCT06427187 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Thromboelastometry and Ischemic Stroke (ThromboPredict)
NCT04870684 ·Status: UNKNOWN
-
Dutch Intracerebral Hemorrhage Surgery Trial Pilot Study
NCT03608423 ·Status: COMPLETED ·Phase: NA
-
Endovascular Treatment Beyond 24 Hours for Acute Ischemic Stroke Caused by Anterior Circulation Large Vessel Stenosis
NCT06959199 ·Status: RECRUITING ·Phase: NA
-
Investigation and Study on the Status of Endovascular Therapy in Acute Ischemic Stroke Ischemic Stroke
NCT03909438 ·Status: UNKNOWN