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Huntington's Disease Young Adult Study 2.0

NCT06391619 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 154

Last updated 2024-04-30

No results posted yet for this study

Summary

The goal of this observational study is to learn about the first signs of disease in young adult carriers of the gene for Huntington's disease. The main questions to answer are:

* what are the earliest signs of the disease?
* can we identify the best time to intervene with treatment to prevent or delay onset of symptoms?
* can we identify the most reliable markers of disease for use in prevention trials?

Participants will undergo the following assessments:

* clinical examination
* cognitive and neuropsychiatric testing
* brain imaging
* biofluid sampling

Researchers will compare gene carriers with matched controls to see if any of these measures show evidence of early disease effects.

Conditions

  • Huntington Disease

Interventions

OTHER

No intervention

Study is observational

Sponsors & Collaborators

  • University of Iowa

    collaborator OTHER

  • University of Cambridge

    collaborator OTHER

  • University of Glasgow

    collaborator OTHER

  • University College, London

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
47 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-06
Primary Completion
2025-12-01
Completion
2025-12-01

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06391619 on ClinicalTrials.gov