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Executive Function in Preterm Born Children: An Integrative Approach From Genetics to Brain Function

NCT01615523 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2012-06-08

No results posted yet for this study

Summary

Hd-EEG and MRI measures are used to study the maturation of functional networks in order to identify the neural circuits underlying executive and memory processes in children born preterm. It will be determined whether children born preterm with executive function deficits will have an abnormal connectivity between basal ganglia and cortex due to WM injury. Moreover, the development of hd-EEG activity during sleep (coherence and travelling waves) and brain maturation of children and adolescents born preterm will be compared with the respective measures in healthy controls. This is of eminent importance as it helps to understand the nature of executive function and hence, it may help to develop neuroprotective strategies to prevent executive function deficits in these infants.

Conditions

  • Preterm Infants

Interventions

OTHER

MRI, EEG and cognitive testing

Sleep EEG and one MRI, executive function testing using Strrop test, BRIEF questionnaire and CantabEclipse

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Cornelia F Hagmann, MD · University Hospital Zurich, Division of Neonatology

Eligibility

Min Age
10 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-09-30
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01615523 on ClinicalTrials.gov