Using NLP and Neural Networks to Autonomously Identify Severe Asthma and Determine Study Eligibility in a Large Healthcare System
NCT06389058 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 31795
Last updated 2026-04-22
Summary
The study aims to to use new technologies (ML, AI, NLP), to autonomously identify moderate to severe asthma populations within an EHR system, describe differences in treatment patterns across different populations, and determine trial eligibility.
Primary Objectives Please ensure you detail primary objectives Aim 1. Determine and validate a diagnosis of severe asthma (SA) using predictive features obtained from the Scripps Health EHR.
* Aim 1a: Use ML applied to structured EHR data to predict SA. Use the opinion of 2 specialty-trained physicians and ATS guidelines to determine model accuracy.
* Aim 1b: Use NLP applied to unstructured text to predict SA. Determine model accuracy as above in Aim 1a.
* Aim 1c: Use a combination of ML applied to structured data to predict SA. Determine model accuracy as above in Aim 1a.
Conditions
Interventions
- OTHER
-
Recommendation for the diagnoses and treatment of Severe Asthma
No intervention planned in this phase for the patients. Recommendations to be developed for healthcare and condition.
Sponsors & Collaborators
- collaborator INDUSTRY
-
Scripps Health
collaborator OTHER -
Modena Allergy + Asthma, La Jolla, CA
collaborator UNKNOWN -
University of California, San Diego
collaborator OTHER -
San Diego State University
lead OTHER
Principal Investigators
-
yusuf Ozturk, Ph.D. · San Diego State University
Eligibility
- Min Age
- 6 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-01
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- United States
Study Locations
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