Patterns of Neurocircuitry Activation In Severe Asthma

NCT03230188 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2019-01-24

No results posted yet for this study

Summary

The overall purpose of the study is to compare the patterns of neurocircuitry activation in severe asthmatics vs. mild to moderate and healthy controls. The Investigators hypothesize that neurocircuitry activation increases with asthma severity, producing different neurocircuitry patterns for severe asthmatics than those of mild to moderate asthmatics or non-asthmatics.

Conditions

  • Lung Diseases

Interventions

OTHER

functional Magnetic Resonance Imaging (research grade)

Subjects will undergo a simulated and actual functional Magnetic Resonance Imaging scan.

OTHER

Cognitive Function Testing (non-diagnostic)

Subjects will take non-diagnostic cognitive function tests

OTHER

Asthma and Psychological Questionnaires (non-diagnostic)

Subjects will fill out asthma and psychological questionnaires (non-diagnostic)

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH
  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH
  • University of Wisconsin, Madison

    lead OTHER

Principal Investigators

  • William W Busse, MD · The University of Wisconsin School of Medicine and Public Health

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-08-01
Primary Completion
2018-06-17
Completion
2018-06-17

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03230188 on ClinicalTrials.gov