Idiopathic Generalized Epilepsy Syndromes
NCT06388174 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2025-08-27
Summary
The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of anti-seizure medications (ASMs), and provides prognostic guidance.
According to the new ILAE definition in 2022, the study aims to describe the clinical features, electroencephalographic, imaging findings and long-term prognosis.
Conditions
- Epilepsy
- Epilepsy, Idiopathic Generalized
Sponsors & Collaborators
-
Shen Chun-Hong
lead OTHER
Principal Investigators
-
Chunhong Shen · Second Affiliated Hospital, School of Medicine, Zhejiang University
Eligibility
- Min Age
- 4 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-01-01
- Primary Completion
- 2026-12-31
- Completion
- 2033-12-31
Countries
- China
Study Locations
More Related Trials
-
Biology of Juvenile Myoclonic Epilepsy
NCT03400371 ·Status: RECRUITING
-
Gene Expression Changes of Brain Tissue in Human Temporal Lobe Epilepsy With Hippocampal Sclerosis
NCT04917939 ·Status: ACTIVE_NOT_RECRUITING
-
Epilepsy Prevalence and Intervention Study in Zhejiang Province, China
NCT04944641 ·Status: UNKNOWN ·Phase: NA
-
Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome
NCT05374824 ·Status: RECRUITING
-
Genetic Diagnosis and Personalized Medicine for Patients With Epilepsy
NCT06321822 ·Status: RECRUITING ·Phase: NA
-
Clinical-genetic Investigations in Children With Early Infantile Epilepsies
NCT01357707 ·Status: COMPLETED
-
A Prospective, Remote Observational Study in Pediatric Participants With Early-Onset SCN2A-Developmental and Epileptic Encephalopathy
NCT05407727 ·Status: COMPLETED
-
Novel Network Analysis of Intracranial Stereoelectroencephalography
NCT03916848 ·Status: UNKNOWN ·Phase: NA
-
Association Between Ferroptosis and Epilepsy
NCT05269901 ·Status: COMPLETED
-
Big Data Construction and Biological Etiological Epidemiology Study of Children Epilepsy in China
NCT02969213 ·Status: UNKNOWN
-
Effect of the New Definition of Epilepsies of the ILAE of 2014 on the Diagnosis After the First Seizure
NCT06836687 ·Status: RECRUITING
-
Neonatal Seizures: Semiology, Etiology, Therapy and Prognosis Correlations
NCT06308185 ·Status: ACTIVE_NOT_RECRUITING
-
Genetics of Rolandic Epilepsy
NCT00282854 ·Status: COMPLETED
-
Antibodies Causing Epilepsy Syndromes: The ACES Study.
NCT02802475 ·Status: COMPLETED
-
Rolandic Epilepsy Genomewide Association International Study
NCT03547050 ·Status: COMPLETED
-
Efficacy and Safety of Adjunctive Zonisamide in Myoclonic Seizures Associated With Idiopathic Generalised Epilepsy
NCT00693017 ·Status: TERMINATED ·Phase: PHASE3
-
A Cohort Study on the Prognosis of Neonatal KCNQ2 Gene-associated Epileptic Encephalopathy
NCT03934268 ·Status: UNKNOWN
-
Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis
NCT06701084 ·Status: RECRUITING ·Phase: NA
-
A Clinical Study of Children With Status Epilepticus in China
NCT03378687 ·Status: UNKNOWN
-
Low Glycemic Index Diet Therapy in Children With Refractory Epilepsy
NCT01645072 ·Status: UNKNOWN ·Phase: PHASE3
-
Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
NCT02890641 ·Status: RECRUITING
-
Seizures and Traumatic Brain Injury Rehabilitation
NCT05823168 ·Status: COMPLETED
-
A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures
NCT00465517 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating NPT 2042 Versus Placebo in Subjects Aged 16-75 Years With Genetic Generalized Epilepsy (GGE) and Absence Seizures
NCT06769659 ·Status: RECRUITING ·Phase: PHASE2
-
A Clinical Trial With a Self-controlled, Multicenter, Pediatric EEG Intelligent Analysis System to Assist in Diagnosis
NCT06918457 ·Status: NOT_YET_RECRUITING