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Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia

NCT06979141 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2025-06-11

No results posted yet for this study

Summary

The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.

Conditions

Interventions

DRUG

Dexmedetomidine

Patients will receive 0.5 μg/kg dexmedetomidine in 10ml normal saline 10 min before the end of surgery.

DRUG

Magnesium sulfate

Patients will receive 30 mg/kg IV magnesium sulfate 50% 10 min before the end of surgery.

DRUG

Lidocaine

Patients will receive lidocaine 1.5 mg/kg lidocaine 10 min before the end of surgery.

DRUG

normal saline

Patients will receive 10 ml normal saline 10 min before the end of surgery.

Sponsors & Collaborators

  • Al-Azhar University

    lead OTHER

Principal Investigators

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-02
Primary Completion
2026-06-01
Completion
2026-08-01

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06979141 on ClinicalTrials.gov