Identification Of High-risk Coronary Plaques By Multimodal Intravascular Imaging

Summary

This study is a multicenter prospective observational clinical study, which will be conducted in 11 hospitals, and approximately 500 subjects will be enrolled. Plaque morphology and stability of non-culprit lesions were assessed by intravascular ultrasound (IVUS) and optical coherence tomography-near-infrared spectroscopy (OCT) after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS). Plaques were grouped according to high-risk or non-high-risk. Clinical follow-up was conducted after PCI.

Conditions

• Coronary Arterial Disease (CAD)
• Acute Coronary Syndromes

Interventions

DIAGNOSTIC_TEST

Assessment of plaque morphology, structure, and stability in non-culprit lesions

Assessment of plaque morphology, structure, and stability in non-culprit lesions based on intravascular ultrasound and optical coherence tomography-near-infrared spectroscopy imaging technology.

Sponsors & Collaborators

• Chinese PLA General Hospital

  lead OTHER

Principal Investigators

• Yun Dai Chen, MD, PHD · People's Liberation Army General Hospital

• Yong Zeng, PD · Beijing Anzhen Hospital

• Lei Song · Chinese Academy of Medical Sciences, Fuwai Hospital

• Jun Jiang, MD · Second Affiliated Hospital, School of Medicine, Zhejiang University

• Yuquan He, MD · China-Japan Union Hospital, Jilin University

• Wei Liu, MD · Beijing Jishuitan Hospital

• Da Yin, MD · Shenzhen People's Hospital

• Yining Yang, MD · People's Hospital of Xinjiang Uygur Autonomous Region

• Jie Deng, MD · Xi'an Jiaotong University Second Affiliated Hospital

• Ning Yang, MD · Tianjin Chest Hospital

• Hua Yan · Wuhan Asian Heart Hospital

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-11-30

Primary Completion

2027-12-31

Completion

2031-12-31

Countries

• China

Study Locations